LINC02086

Summary

LINC02086 (long intergenic non-protein coding RNA 2086, HGNC:52936) is a long non-coding RNA gene on chromosome 17q21.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52936
Approved symbol	LINC02086
Name	long intergenic non-protein coding RNA 2086
Location	17q21.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000244649
Ensembl biotype	lncRNA
Entrez	105371809
RNAcentral	URS00028539FA — lncRNA, 3731 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000478824, ENST00000492522, ENST00000575202, ENST00000628006, ENST00000628749, ENST00000629037, ENST00000669176, ENST00000765376, ENST00000765377, ENST00000765378

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000478824 — 2 exons

Exon	Start	End
ENSE00001882786	48705203	48705350
ENSE00001939507	48706059	48707346

Expression profiles

Bgee: expression breadth ubiquitous, 104 present calls, max score 92.66.

Top tissues by expression

207 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
mucosa of transverse colon	UBERON:0004991	92.66	gold quality
ileal mucosa	UBERON:0000331	91.25	gold quality
rectum	UBERON:0001052	85.52	gold quality
transverse colon	UBERON:0001157	84.65	gold quality
colonic epithelium	UBERON:0000397	82.18	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.37	gold quality
colonic mucosa	UBERON:0000317	78.11	gold quality
kidney epithelium	UBERON:0004819	76.52	gold quality
mucosa of sigmoid colon	UBERON:0004993	76.30	gold quality
small intestine Peyer’s patch	UBERON:0003454	74.26	gold quality
large intestine	UBERON:0000059	73.32	gold quality
colon	UBERON:0001155	73.07	gold quality
intestine	UBERON:0000160	72.62	gold quality
tibialis anterior	UBERON:0001385	72.60	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	71.99	gold quality
small intestine	UBERON:0002108	70.86	gold quality
cardiac muscle of right atrium	UBERON:0003379	68.97	gold quality
metanephros cortex	UBERON:0010533	68.97	gold quality
vermiform appendix	UBERON:0001154	68.76	gold quality
left ventricle myocardium	UBERON:0006566	68.58	gold quality
caecum	UBERON:0001153	68.12	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.15	gold quality
pancreatic ductal cell	CL:0002079	66.63	silver quality
metanephros	UBERON:0000081	66.53	gold quality
granulocyte	CL:0000094	66.13	gold quality
kidney	UBERON:0002113	65.25	gold quality
cortex of kidney	UBERON:0001225	65.02	gold quality
adult mammalian kidney	UBERON:0000082	64.69	gold quality
myocardium	UBERON:0002349	64.65	gold quality
epithelial cell of pancreas	CL:0000083	64.16	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.72

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC02086 promotes cell viability and inhibits cell apoptosis in breast cancer by sponging miR-6757-5p and up-regulating EPHA2. (PMID:38008720)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.