LINC02089

Summary

LINC02089 (long intergenic non-protein coding RNA 2089, HGNC:52940) is a long non-coding RNA gene on chromosome 17q22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52940
Approved symbol	LINC02089
Name	long intergenic non-protein coding RNA 2089
Location	17q22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226364
Ensembl biotype	lncRNA
Entrez	105371831
RNAcentral	URS00007C6ECB — lncRNA, 682 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 15 lncRNA

ENST00000412360, ENST00000623702, ENST00000649605, ENST00000715800, ENST00000715801, ENST00000741187, ENST00000753155, ENST00000753156, ENST00000753157, ENST00000753158, ENST00000753159, ENST00000753160, ENST00000753161, ENST00000753162, ENST00000753163

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412360 — 3 exons

Exon	Start	End
ENSE00001749053	52898434	52898506
ENSE00004100015	52899331	52899603
ENSE00004100024	52862065	52862471

Expression profiles

Bgee: expression breadth broad, 37 present calls, max score 90.38.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0487 / max 20.7499, expressed in 14 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
161752	0.0487	14
161753	0.0034	3

Top tissues by expression

37 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	90.38	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	72.82	gold quality
testis	UBERON:0000473	65.75	gold quality
left testis	UBERON:0004533	64.55	gold quality
right testis	UBERON:0004534	63.11	gold quality
hindlimb stylopod muscle	UBERON:0004252	61.69	gold quality
monocyte	CL:0000576	60.64	gold quality
multicellular organism	UBERON:0000468	59.08	gold quality
skeletal muscle tissue	UBERON:0001134	57.17	gold quality
muscle of leg	UBERON:0001383	51.15	gold quality
islet of Langerhans	UBERON:0000006	49.74	gold quality
gastrocnemius	UBERON:0001388	48.32	gold quality
blood	UBERON:0000178	46.39	silver quality
Ammon’s horn	UBERON:0001954	43.85	silver quality
tibial nerve	UBERON:0001323	42.95	gold quality
tibial artery	UBERON:0007610	41.68	silver quality
anterior cingulate cortex	UBERON:0009835	41.28	silver quality
vagina	UBERON:0000996	41.16	silver quality
stomach	UBERON:0000945	40.57	silver quality
lower esophagus muscularis layer	UBERON:0035833	40.26	silver quality
heart left ventricle	UBERON:0002084	40.19	silver quality
left coronary artery	UBERON:0001626	40.18	silver quality
amygdala	UBERON:0001876	40.07	silver quality
tonsil	UBERON:0002372	39.64	silver quality
esophagus mucosa	UBERON:0002469	39.43	silver quality
ascending aorta	UBERON:0001496	39.40	silver quality
body of stomach	UBERON:0001161	39.30	silver quality
muscle layer of sigmoid colon	UBERON:0035805	38.68	silver quality
thyroid gland	UBERON:0002046	38.55	silver quality
body of uterus	UBERON:0009853	38.40	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.