LINC02105

Summary

LINC02105 (long intergenic non-protein coding RNA 2105, HGNC:52960) is a long non-coding RNA gene on chromosome 5q11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52960
Approved symbol	LINC02105
Name	long intergenic non-protein coding RNA 2105
Location	5q11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250447
Ensembl biotype	lncRNA
Entrez	105378966
RNAcentral	URS0000BC45C7 — lncRNA, 1840 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000504552, ENST00000511953, ENST00000671867, ENST00000672395, ENST00000672960, ENST00000673580, ENST00000673597, ENST00000784702, ENST00000784703

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000504552 — 4 exons

Exon	Start	End
ENSE00002022772	53783967	53784130
ENSE00002032972	53785080	53785144
ENSE00004159724	53776050	53777286
ENSE00004159725	53819556	53819702

Expression profiles

Bgee: expression breadth broad, 26 present calls, max score 78.33.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4251 / max 36.9703, expressed in 70 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
61638	0.4251	70

Top tissues by expression

26 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.33	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	58.46	gold quality
right ovary	UBERON:0002118	54.20	gold quality
testis	UBERON:0000473	52.85	gold quality
blood	UBERON:0000178	52.52	silver quality
left testis	UBERON:0004533	52.05	gold quality
prefrontal cortex	UBERON:0000451	51.92	gold quality
multicellular organism	UBERON:0000468	51.47	gold quality
right testis	UBERON:0004534	49.71	gold quality
gastrocnemius	UBERON:0001388	48.10	gold quality
islet of Langerhans	UBERON:0000006	47.42	gold quality
heart	UBERON:0000948	47.13	silver quality
adult mammalian kidney	UBERON:0000082	45.90	silver quality
left adrenal gland cortex	UBERON:0035825	45.47	silver quality
adrenal gland	UBERON:0002369	44.81	silver quality
left adrenal gland	UBERON:0001234	43.99	silver quality
spleen	UBERON:0002106	42.89	silver quality
left ovary	UBERON:0002119	40.92	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	40.40	silver quality
skin of abdomen	UBERON:0001416	39.32	silver quality
esophagus mucosa	UBERON:0002469	38.68	silver quality
body of stomach	UBERON:0001161	38.08	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	37.84	silver quality
hypothalamus	UBERON:0001898	37.48	silver quality
lower esophagus muscularis layer	UBERON:0035833	37.42	silver quality
tibial nerve	UBERON:0001323	31.23	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.