LINC02121

Summary

LINC02121 (long intergenic non-protein coding RNA 2121, HGNC:52977) is a long non-coding RNA gene on chromosome 5p15.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52977
Approved symbol	LINC02121
Name	long intergenic non-protein coding RNA 2121
Location	5p15.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250529
Ensembl biotype	lncRNA
Entrez	105374631
RNAcentral	URS0000A771EE — lncRNA, 446 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000507950, ENST00000736131, ENST00000736132, ENST00000736133

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000507950 — 2 exons

Exon	Start	End
ENSE00004069114	5078204	5078495
ENSE00004069116	5068559	5069515

Expression profiles

Bgee: expression breadth broad, 33 present calls, max score 74.99.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0226 / max 4.0831, expressed in 17 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
60849	0.0226	17

Top tissues by expression

43 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adult mammalian kidney	UBERON:0000082	74.99	gold quality
kidney	UBERON:0002113	74.33	gold quality
quadriceps femoris	UBERON:0001377	65.49	gold quality
cerebellar vermis	UBERON:0004720	64.61	gold quality
cortex of kidney	UBERON:0001225	64.10	gold quality
anterior cingulate cortex	UBERON:0009835	63.76	gold quality
liver	UBERON:0002107	60.13	gold quality
spinal cord	UBERON:0002240	59.60	silver quality
bone marrow	UBERON:0002371	59.48	silver quality
pancreas	UBERON:0001264	59.32	silver quality
skeletal muscle tissue	UBERON:0001134	59.30	silver quality
heart	UBERON:0000948	59.12	silver quality
thymus	UBERON:0002370	59.12	silver quality
prostate gland	UBERON:0002367	57.55	silver quality
blood	UBERON:0000178	57.50	gold quality
subcutaneous adipose tissue	UBERON:0002190	57.03	gold quality
monocyte	CL:0000576	56.70	gold quality
metanephros cortex	UBERON:0010533	55.50	gold quality
intestine	UBERON:0000160	53.56	gold quality
endometrium	UBERON:0001295	52.71	gold quality
gastrocnemius	UBERON:0001388	50.94	gold quality
multicellular organism	UBERON:0000468	49.60	gold quality
skin of abdomen	UBERON:0001416	49.39	gold quality
caudate nucleus	UBERON:0001873	49.31	silver quality
zone of skin	UBERON:0000014	48.75	gold quality
lung	UBERON:0002048	45.95	silver quality
ovary	UBERON:0000992	45.26	gold quality
omental fat pad	UBERON:0010414	45.09	silver quality
upper lobe of left lung	UBERON:0008952	44.77	silver quality
left ovary	UBERON:0002119	44.69	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.98

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.