LINC02127

Summary

LINC02127 (long intergenic non-protein coding RNA 2127, HGNC:52985) is a long non-coding RNA gene on chromosome 16q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52985
Approved symbol	LINC02127
Name	long intergenic non-protein coding RNA 2127
Location	16q12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261637
Ensembl biotype	lncRNA
Entrez	101927334
RNAcentral	URS00005843C5 — lncRNA, 437 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000563826, ENST00000568607, ENST00000653336, ENST00000657135, ENST00000658899, ENST00000660062

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000563826 — 3 exons

Exon	Start	End
ENSE00002577952	51022220	51022276
ENSE00002629515	51035536	51035784
ENSE00004211552	51017603	51017895

Expression profiles

Bgee: expression breadth broad, 64 present calls, max score 85.71.

Top tissues by expression

64 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.71	gold quality
left testis	UBERON:0004533	73.80	gold quality
right testis	UBERON:0004534	73.12	gold quality
testis	UBERON:0000473	73.11	gold quality
right lobe of liver	UBERON:0001114	61.99	gold quality
liver	UBERON:0002107	61.06	gold quality
multicellular organism	UBERON:0000468	55.87	gold quality
vermiform appendix	UBERON:0001154	55.45	gold quality
blood	UBERON:0000178	52.25	silver quality
prefrontal cortex	UBERON:0000451	52.22	gold quality
tibial nerve	UBERON:0001323	52.13	gold quality
monocyte	CL:0000576	51.13	silver quality
endometrium	UBERON:0001295	51.05	gold quality
heart	UBERON:0000948	48.09	gold quality
right atrium auricular region	UBERON:0006631	48.04	gold quality
gastrocnemius	UBERON:0001388	47.96	gold quality
ectocervix	UBERON:0012249	45.88	gold quality
heart left ventricle	UBERON:0002084	45.79	silver quality
primary visual cortex	UBERON:0002436	45.61	silver quality
kidney	UBERON:0002113	45.50	silver quality
adult mammalian kidney	UBERON:0000082	45.01	silver quality
body of pancreas	UBERON:0001150	44.74	gold quality
cerebellar hemisphere	UBERON:0002245	44.52	silver quality
right hemisphere of cerebellum	UBERON:0014890	43.77	silver quality
tibial artery	UBERON:0007610	43.72	silver quality
metanephros cortex	UBERON:0010533	43.54	gold quality
ovary	UBERON:0000992	42.95	gold quality
stomach	UBERON:0000945	42.69	gold quality
Brodmann (1909) area 9	UBERON:0013540	42.08	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	41.88	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.