LINC02154

Summary

LINC02154 (long intergenic non-protein coding RNA 2154, HGNC:53015) is a long non-coding RNA gene on chromosome Xp22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53015
Approved symbol	LINC02154
Name	long intergenic non-protein coding RNA 2154
Location	Xp22.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	GS1-600G8.5, MALR
Ensembl gene	ENSG00000235385
Ensembl biotype	lncRNA
Entrez	109729169
RNAcentral	URS0000BC43DC — lncRNA, 1439 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000412485, ENST00000443965, ENST00000670053, ENST00000841366, ENST00000841367

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412485 — 3 exons

Exon	Start	End
ENSE00001631918	13266048	13267335
ENSE00001745947	13287429	13287564
ENSE00004265669	13303320	13303413

Expression profiles

Bgee: expression breadth broad, 71 present calls, max score 76.82.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.5825 / max 144.9146, expressed in 141 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
198455	0.5741	138
198454	0.0084	4

Top tissues by expression

71 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
testis	UBERON:0000473	76.82	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.20	silver quality
stromal cell of endometrium	CL:0002255	70.33	gold quality
right lung	UBERON:0002167	66.70	gold quality
lung	UBERON:0002048	61.14	gold quality
ventricular zone	UBERON:0003053	58.55	silver quality
upper lobe of left lung	UBERON:0008952	58.18	gold quality
endometrium	UBERON:0001295	57.83	gold quality
islet of Langerhans	UBERON:0000006	55.96	gold quality
lymph node	UBERON:0000029	54.59	gold quality
blood	UBERON:0000178	52.99	gold quality
myometrium	UBERON:0001296	52.47	gold quality
placenta	UBERON:0001987	52.29	gold quality
prefrontal cortex	UBERON:0000451	51.63	gold quality
subcutaneous adipose tissue	UBERON:0002190	50.42	gold quality
right adrenal gland cortex	UBERON:0035827	50.01	gold quality
vermiform appendix	UBERON:0001154	49.53	gold quality
urinary bladder	UBERON:0001255	49.43	gold quality
thoracic mammary gland	UBERON:0005200	49.04	gold quality
left adrenal gland cortex	UBERON:0035825	48.89	gold quality
body of uterus	UBERON:0009853	48.87	gold quality
Brodmann (1909) area 9	UBERON:0013540	48.87	gold quality
right adrenal gland	UBERON:0001233	48.79	gold quality
adipose tissue	UBERON:0001013	48.55	gold quality
multicellular organism	UBERON:0000468	48.03	gold quality
stomach	UBERON:0000945	47.84	gold quality
left adrenal gland	UBERON:0001234	47.23	gold quality
body of stomach	UBERON:0001161	47.11	gold quality
prostate gland	UBERON:0002367	47.09	gold quality
minor salivary gland	UBERON:0001830	46.96	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.78

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Bioinformatics analysis and experimental validation of cuproptosis-related lncRNA LINC02154 in clear cell renal cell carcinoma. (PMID:36797708)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.