LINC02166

Summary

LINC02166 (long intergenic non-protein coding RNA 2166, HGNC:53027) is a long non-coding RNA gene on chromosome 16q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53027
Approved symbol	LINC02166
Name	long intergenic non-protein coding RNA 2166
Location	16q24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260259
Ensembl biotype	lncRNA
Entrez	105371416
RNAcentral	URS00026A22A1 — lncRNA, 802 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000567544, ENST00000749100, ENST00000749101, ENST00000749102, ENST00000749103, ENST00000749104, ENST00000749105

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000567544 — 3 exons

Exon	Start	End
ENSE00002602418	89685301	89685675
ENSE00004092470	89682507	89682842
ENSE00004092476	89686447	89686600

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 91.06.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1435 / max 21.2010, expressed in 44 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
158641	0.1435	44

Top tissues by expression

126 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	91.06	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.16	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	83.17	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.36	silver quality
left testis	UBERON:0004533	74.25	gold quality
right lobe of liver	UBERON:0001114	73.67	gold quality
testis	UBERON:0000473	73.35	gold quality
right testis	UBERON:0004534	73.29	gold quality
fallopian tube	UBERON:0003889	70.93	gold quality
liver	UBERON:0002107	68.98	gold quality
adult mammalian kidney	UBERON:0000082	68.07	gold quality
kidney	UBERON:0002113	67.07	gold quality
ventricular zone	UBERON:0003053	66.13	gold quality
cortex of kidney	UBERON:0001225	65.00	gold quality
metanephros cortex	UBERON:0010533	63.43	gold quality
placenta	UBERON:0001987	61.85	gold quality
left uterine tube	UBERON:0001303	61.66	gold quality
right lung	UBERON:0002167	61.64	gold quality
right lobe of thyroid gland	UBERON:0001119	61.00	gold quality
upper lobe of left lung	UBERON:0008952	60.82	gold quality
hypothalamus	UBERON:0001898	60.76	gold quality
pituitary gland	UBERON:0000007	60.43	gold quality
lung	UBERON:0002048	60.26	gold quality
endometrium	UBERON:0001295	60.25	gold quality
thyroid gland	UBERON:0002046	60.25	gold quality
ganglionic eminence	UBERON:0004023	60.19	gold quality
Ammon’s horn	UBERON:0001954	60.18	gold quality
adenohypophysis	UBERON:0002196	60.06	gold quality
left lobe of thyroid gland	UBERON:0001120	60.04	gold quality
skeletal muscle tissue	UBERON:0001134	59.84	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	9.31

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.