LINC02177

Summary

LINC02177 (long intergenic non-protein coding RNA 2177, HGNC:53039) is a long non-coding RNA gene on chromosome 16p13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53039
Approved symbol	LINC02177
Name	long intergenic non-protein coding RNA 2177
Location	16p13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261617
Ensembl biotype	lncRNA
Entrez	101927009
RNAcentral	URS00004A6B42 — lncRNA, 5298 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 65 — 65 lncRNA

ENST00000564305, ENST00000570038, ENST00000634367, ENST00000652999, ENST00000653393, ENST00000653539, ENST00000654659, ENST00000657043, ENST00000657081, ENST00000658002, ENST00000658945, ENST00000659212, ENST00000659300, ENST00000659345, ENST00000659361, ENST00000660662, ENST00000660678, ENST00000661227, ENST00000663435, ENST00000663910, ENST00000664064, ENST00000664399, ENST00000665404, ENST00000665919, ENST00000666769, ENST00000667033, ENST00000667976, ENST00000671144, ENST00000701200, ENST00000701702, ENST00000784364, ENST00000784365, ENST00000784366, ENST00000784367, ENST00000784368, ENST00000784369, ENST00000784370, ENST00000784371, ENST00000784372, ENST00000784373, ENST00000784374, ENST00000784375, ENST00000784376, ENST00000784377, ENST00000784378, ENST00000784379, ENST00000784380, ENST00000784381, ENST00000784382, ENST00000784383, ENST00000784384, ENST00000784503, ENST00000784504, ENST00000784505, ENST00000784506, ENST00000784507, ENST00000784508, ENST00000784509, ENST00000784510, ENST00000784511, ENST00000784512, ENST00000784513, ENST00000784514, ENST00000784660, ENST00000784661

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000564305 — 3 exons

Exon	Start	End
ENSE00002588744	9401730	9401783
ENSE00002590101	9403043	9408093
ENSE00002626034	9355588	9355780

Expression profiles

Bgee: expression breadth ubiquitous, 102 present calls, max score 78.93.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2221 / max 28.7072, expressed in 82 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
152685	0.2159	80
152684	0.0062	1

Top tissues by expression

102 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.93	gold quality
duodenum	UBERON:0002114	67.28	gold quality
liver	UBERON:0002107	61.50	gold quality
putamen	UBERON:0001874	61.15	gold quality
calcaneal tendon	UBERON:0003701	61.15	gold quality
sural nerve	UBERON:0015488	59.42	silver quality
small intestine	UBERON:0002108	58.55	gold quality
right lobe of liver	UBERON:0001114	57.93	gold quality
substantia nigra	UBERON:0002038	57.92	gold quality
primary visual cortex	UBERON:0002436	57.34	gold quality
small intestine Peyer’s patch	UBERON:0003454	57.17	gold quality
temporal lobe	UBERON:0001871	56.89	gold quality
amygdala	UBERON:0001876	56.80	gold quality
caudate nucleus	UBERON:0001873	56.19	gold quality
hindlimb stylopod muscle	UBERON:0004252	56.09	silver quality
skeletal muscle tissue	UBERON:0001134	55.53	gold quality
Ammon’s horn	UBERON:0001954	55.51	gold quality
heart left ventricle	UBERON:0002084	54.77	gold quality
hypothalamus	UBERON:0001898	54.33	gold quality
prefrontal cortex	UBERON:0000451	54.32	gold quality
cortex of kidney	UBERON:0001225	54.16	gold quality
body of pancreas	UBERON:0001150	53.76	gold quality
corpus callosum	UBERON:0002336	53.72	gold quality
intestine	UBERON:0000160	53.48	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	53.30	gold quality
brain	UBERON:0000955	53.06	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	52.91	gold quality
endometrium	UBERON:0001295	52.65	gold quality
superior frontal gyrus	UBERON:0002661	52.41	gold quality
pancreas	UBERON:0001264	52.31	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.07

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.