LINC02180

Summary

LINC02180 (long intergenic non-protein coding RNA 2180, HGNC:53042) is a long non-coding RNA gene on chromosome 16q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53042
Approved symbol	LINC02180
Name	long intergenic non-protein coding RNA 2180
Location	16q12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261749
Ensembl biotype	lncRNA
Entrez	102467079
RNAcentral	URS000075C65C — lncRNA, 1009 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 22 — 22 lncRNA

ENST00000566439, ENST00000568711, ENST00000656714, ENST00000658449, ENST00000659261, ENST00000659332, ENST00000660788, ENST00000664235, ENST00000668292, ENST00000670037, ENST00000670505, ENST00000670615, ENST00000717481, ENST00000817132, ENST00000817133, ENST00000817134, ENST00000817135, ENST00000817136, ENST00000817137, ENST00000817138, ENST00000817139, ENST00000817140

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000566439 — 3 exons

Exon	Start	End
ENSE00002587050	52094959	52095073
ENSE00003866375	52098300	52099078
ENSE00003866551	52085218	52085406

Expression profiles

Bgee: expression breadth broad, 27 present calls, max score 91.04.

Top tissues by expression

172 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.04	gold quality
sperm	CL:0000019	87.28	gold quality
buccal mucosa cell	CL:0002336	76.65	silver quality
cardiac muscle of right atrium	UBERON:0003379	75.38	gold quality
left ventricle myocardium	UBERON:0006566	75.25	gold quality
right testis	UBERON:0004534	70.82	gold quality
left testis	UBERON:0004533	70.57	gold quality
testis	UBERON:0000473	69.01	gold quality
kidney epithelium	UBERON:0004819	66.07	gold quality
pancreatic ductal cell	CL:0002079	65.29	silver quality
myocardium	UBERON:0002349	61.45	gold quality
nasal cavity epithelium	UBERON:0005384	58.69	gold quality
tibialis anterior	UBERON:0001385	57.52	silver quality
ileal mucosa	UBERON:0000331	55.99	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	55.88	gold quality
epithelial cell of pancreas	CL:0000083	55.29	gold quality
islet of Langerhans	UBERON:0000006	54.79	gold quality
corpus epididymis	UBERON:0004359	54.32	gold quality
monocyte	CL:0000576	53.75	silver quality
upper arm skin	UBERON:0004263	53.52	gold quality
quadriceps femoris	UBERON:0001377	53.09	gold quality
deltoid	UBERON:0001476	52.55	gold quality
vastus lateralis	UBERON:0001379	52.51	gold quality
cerebellar vermis	UBERON:0004720	51.94	gold quality
metanephros	UBERON:0000081	50.04	gold quality
gastrocnemius	UBERON:0001388	49.39	silver quality
adult mammalian kidney	UBERON:0000082	48.30	gold quality
adult organism	UBERON:0007023	48.18	silver quality
skeletal muscle tissue	UBERON:0001134	47.82	gold quality
pancreas	UBERON:0001264	47.82	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.