LINC02181

Summary

LINC02181 (long intergenic non-protein coding RNA 2181, HGNC:53043) is a long non-coding RNA gene on chromosome 16q24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53043
Approved symbol	LINC02181
Name	long intergenic non-protein coding RNA 2181
Location	16q24.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232190
Ensembl biotype	lncRNA
Entrez	440390
RNAcentral	URS00007C875C — lncRNA, 4083 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000430050, ENST00000664021, ENST00000767936, ENST00000767937

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000430050 — 3 exons

Exon	Start	End
ENSE00001731048	87062752	87063991
ENSE00002237697	87061058	87061184
ENSE00002320944	87057784	87060499

Expression profiles

Bgee: expression breadth broad, 41 present calls, max score 74.22.

Top tissues by expression

41 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.22	silver quality
ganglionic eminence	UBERON:0004023	57.21	silver quality
muscle of leg	UBERON:0001383	55.11	silver quality
lymph node	UBERON:0000029	51.00	silver quality
blood	UBERON:0000178	50.00	silver quality
thyroid gland	UBERON:0002046	48.80	silver quality
prefrontal cortex	UBERON:0000451	47.83	silver quality
urinary bladder	UBERON:0001255	46.22	silver quality
pituitary gland	UBERON:0000007	45.59	gold quality
cerebellar hemisphere	UBERON:0002245	43.23	silver quality
tibial artery	UBERON:0007610	42.85	gold quality
popliteal artery	UBERON:0002250	42.81	gold quality
adult mammalian kidney	UBERON:0000082	42.80	gold quality
esophagus mucosa	UBERON:0002469	42.51	silver quality
small intestine Peyer’s patch	UBERON:0003454	42.38	silver quality
islet of Langerhans	UBERON:0000006	42.36	silver quality
metanephros cortex	UBERON:0010533	42.24	silver quality
right hemisphere of cerebellum	UBERON:0014890	42.05	silver quality
right adrenal gland	UBERON:0001233	41.98	silver quality
thoracic aorta	UBERON:0001515	41.59	silver quality
ascending aorta	UBERON:0001496	41.40	silver quality
descending thoracic aorta	UBERON:0002345	41.30	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	40.95	gold quality
subcutaneous adipose tissue	UBERON:0002190	40.79	silver quality
tibial nerve	UBERON:0001323	40.64	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	39.57	silver quality
lung	UBERON:0002048	39.56	silver quality
adrenal gland	UBERON:0002369	38.85	silver quality
right lung	UBERON:0002167	38.66	silver quality
fundus of stomach	UBERON:0001160	38.03	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.44

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.