LINC02185

Summary

LINC02185 (long intergenic non-protein coding RNA 2185, HGNC:53047) is a long non-coding RNA gene on chromosome 16p13.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53047
Approved symbol	LINC02185
Name	long intergenic non-protein coding RNA 2185
Location	16p13.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000262097
Ensembl biotype	lncRNA
Entrez	101927311
RNAcentral	URS000075E017 — lncRNA, 766 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000575424, ENST00000576797, ENST00000654412, ENST00000662675, ENST00000668908, ENST00000814611, ENST00000814612, ENST00000814613, ENST00000814614, ENST00000814615, ENST00000814616

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000575424 — 4 exons

Exon	Start	End
ENSE00002658224	14013372	14013458
ENSE00003853312	14009968	14010145
ENSE00004215739	14008255	14009797
ENSE00004215749	14015862	14016061

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 80.86.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2685 / max 28.7072, expressed in 133 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
156359	0.2685	133

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
olfactory segment of nasal mucosa	UBERON:0005386	80.86	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.59	gold quality
apex of heart	UBERON:0002098	76.02	gold quality
subcutaneous adipose tissue	UBERON:0002190	74.93	gold quality
skeletal muscle tissue	UBERON:0001134	73.72	gold quality
placenta	UBERON:0001987	73.29	gold quality
right lung	UBERON:0002167	72.82	gold quality
muscle of leg	UBERON:0001383	72.66	gold quality
calcaneal tendon	UBERON:0003701	72.51	gold quality
gastrocnemius	UBERON:0001388	72.44	gold quality
lower esophagus muscularis layer	UBERON:0035833	72.37	gold quality
lower esophagus	UBERON:0013473	72.24	gold quality
muscle tissue	UBERON:0002385	71.75	gold quality
adipose tissue	UBERON:0001013	71.56	gold quality
monocyte	CL:0000576	71.55	gold quality
leukocyte	CL:0000738	70.85	gold quality
upper lobe of left lung	UBERON:0008952	70.83	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	70.73	gold quality
descending thoracic aorta	UBERON:0002345	70.58	gold quality
thoracic mammary gland	UBERON:0005200	70.43	gold quality
lung	UBERON:0002048	69.46	gold quality
heart left ventricle	UBERON:0002084	69.37	gold quality
right adrenal gland cortex	UBERON:0035827	69.27	gold quality
right adrenal gland	UBERON:0001233	68.90	gold quality
hindlimb stylopod muscle	UBERON:0004252	68.52	gold quality
mucosa of stomach	UBERON:0001199	68.41	gold quality
thoracic aorta	UBERON:0001515	68.38	gold quality
left adrenal gland	UBERON:0001234	68.34	gold quality
ascending aorta	UBERON:0001496	68.04	gold quality
smooth muscle tissue	UBERON:0001135	67.97	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	8.49

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.