LINC02188

Summary

LINC02188 (long intergenic non-protein coding RNA 2188, HGNC:53050) is a long non-coding RNA gene on chromosome 16q24.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53050
Approved symbol	LINC02188
Name	long intergenic non-protein coding RNA 2188
Location	16q24.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261175
Ensembl biotype	lncRNA
Entrez	102724344
RNAcentral	URS0000A776F5 — lncRNA, 658 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 15 lncRNA

ENST00000562064, ENST00000569740, ENST00000647607, ENST00000647615, ENST00000647896, ENST00000648184, ENST00000649094, ENST00000649229, ENST00000649687, ENST00000650018, ENST00000745086, ENST00000745087, ENST00000745088, ENST00000803661, ENST00000803662

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000562064 — 4 exons

Exon	Start	End
ENSE00002580914	86722092	86722147
ENSE00002584080	86737410	86737719
ENSE00002598479	86727868	86727967
ENSE00002607335	86734826	86734909

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 80.41.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1385 / max 13.9919, expressed in 73 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
155467	0.1385	73

Top tissues by expression

112 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
minor salivary gland	UBERON:0001830	80.41	gold quality
saliva-secreting gland	UBERON:0001044	80.19	gold quality
muscle of leg	UBERON:0001383	77.24	gold quality
sural nerve	UBERON:0015488	77.06	gold quality
gastrocnemius	UBERON:0001388	76.79	gold quality
descending thoracic aorta	UBERON:0002345	74.56	gold quality
skeletal muscle tissue	UBERON:0001134	74.18	gold quality
hindlimb stylopod muscle	UBERON:0004252	73.91	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	73.47	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	72.96	gold quality
thoracic aorta	UBERON:0001515	70.14	gold quality
ascending aorta	UBERON:0001496	69.84	gold quality
popliteal artery	UBERON:0002250	69.41	gold quality
tibial artery	UBERON:0007610	69.41	gold quality
tonsil	UBERON:0002372	69.28	gold quality
right coronary artery	UBERON:0001625	68.75	gold quality
ganglionic eminence	UBERON:0004023	67.44	gold quality
thoracic mammary gland	UBERON:0005200	65.91	gold quality
gall bladder	UBERON:0002110	65.10	gold quality
left coronary artery	UBERON:0001626	63.48	gold quality
colonic epithelium	UBERON:0000397	62.77	silver quality
skin of leg	UBERON:0001511	61.03	gold quality
zone of skin	UBERON:0000014	60.68	gold quality
ventricular zone	UBERON:0003053	60.42	gold quality
skin of abdomen	UBERON:0001416	60.17	gold quality
heart left ventricle	UBERON:0002084	58.06	gold quality
tibial nerve	UBERON:0001323	57.28	gold quality
cortex of kidney	UBERON:0001225	56.61	gold quality
heart	UBERON:0000948	55.46	gold quality
multicellular organism	UBERON:0000468	54.83	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.07

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.