LINC02189

Summary

LINC02189 (long intergenic non-protein coding RNA 2189, HGNC:53051) is a long non-coding RNA gene on chromosome 16q24.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53051
Approved symbol	LINC02189
Name	long intergenic non-protein coding RNA 2189
Location	16q24.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260026
Ensembl biotype	lncRNA
Entrez	101928614
RNAcentral	URS0000A77787 — lncRNA, 544 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000563331, ENST00000652314, ENST00000653342, ENST00000659949, ENST00000660139, ENST00000661967, ENST00000667097, ENST00000745300, ENST00000745301, ENST00000745302, ENST00000745303

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000563331 — 2 exons

Exon	Start	End
ENSE00002578897	86721765	86721954
ENSE00002586134	86720688	86721003

Expression profiles

Bgee: expression breadth broad, 87 present calls, max score 94.43.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0188 / max 22.5542, expressed in 3 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
158448	0.0148	3
158449	0.0039	2

Top tissues by expression

193 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	94.43	gold quality
sperm	CL:0000019	93.96	gold quality
left testis	UBERON:0004533	84.03	gold quality
right testis	UBERON:0004534	82.85	gold quality
testis	UBERON:0000473	81.19	gold quality
ganglionic eminence	UBERON:0004023	58.60	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.03	gold quality
minor salivary gland	UBERON:0001830	54.00	gold quality
saliva-secreting gland	UBERON:0001044	52.22	gold quality
mouth mucosa	UBERON:0003729	52.09	gold quality
monocyte	CL:0000576	51.56	silver quality
buccal mucosa cell	CL:0002336	51.52	gold quality
descending thoracic aorta	UBERON:0002345	51.49	gold quality
tibial artery	UBERON:0007610	50.58	gold quality
Brodmann (1909) area 9	UBERON:0013540	50.55	gold quality
popliteal artery	UBERON:0002250	50.50	gold quality
aorta	UBERON:0000947	50.16	gold quality
calcaneal tendon	UBERON:0003701	50.12	silver quality
thoracic aorta	UBERON:0001515	49.94	gold quality
gastrocnemius	UBERON:0001388	49.70	gold quality
ascending aorta	UBERON:0001496	49.60	gold quality
left ovary	UBERON:0002119	49.35	gold quality
right lobe of thyroid gland	UBERON:0001119	49.34	gold quality
adult organism	UBERON:0007023	49.30	gold quality
lower lobe of lung	UBERON:0008949	47.93	silver quality
prefrontal cortex	UBERON:0000451	47.91	gold quality
left coronary artery	UBERON:0001626	46.86	gold quality
anatomical system	UBERON:0000467	45.97	gold quality
coronary artery	UBERON:0001621	45.92	gold quality
material anatomical entity	UBERON:0000465	45.81	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.