LINC02190

Summary

LINC02190 (long intergenic non-protein coding RNA 2190, HGNC:53052) is a long non-coding RNA gene on chromosome 16p11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53052
Approved symbol	LINC02190
Name	long intergenic non-protein coding RNA 2190
Location	16p11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261475
Ensembl biotype	lncRNA
Entrez	105371173
RNAcentral	URS0000BC4404 — lncRNA, 3013 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000567765, ENST00000655928, ENST00000659783, ENST00000662819, ENST00000764174, ENST00000764175, ENST00000764176, ENST00000764177, ENST00000764178, ENST00000764179, ENST00000764180, ENST00000764181, ENST00000764182

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000567765 — 3 exons

Exon	Start	End
ENSE00004120921	31553145	31553596
ENSE00004120926	31542751	31542869
ENSE00004120935	31548984	31549287

Expression profiles

Bgee: expression breadth broad, 41 present calls, max score 70.51.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0120 / max 13.5325, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
157171	0.0120	3

Top tissues by expression

41 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	70.51	gold quality
testis	UBERON:0000473	70.19	gold quality
right testis	UBERON:0004534	68.88	gold quality
sural nerve	UBERON:0015488	64.07	silver quality
multicellular organism	UBERON:0000468	60.90	gold quality
prefrontal cortex	UBERON:0000451	60.17	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	57.86	gold quality
cortex of kidney	UBERON:0001225	55.44	gold quality
blood	UBERON:0000178	54.75	gold quality
tibial nerve	UBERON:0001323	53.69	gold quality
monocyte	CL:0000576	50.95	silver quality
body of pancreas	UBERON:0001150	50.92	gold quality
subcutaneous adipose tissue	UBERON:0002190	48.92	gold quality
body of stomach	UBERON:0001161	48.72	gold quality
gastrocnemius	UBERON:0001388	47.88	gold quality
tibial artery	UBERON:0007610	47.49	gold quality
right atrium auricular region	UBERON:0006631	47.30	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	46.71	gold quality
lower esophagus muscularis layer	UBERON:0035833	45.07	gold quality
esophagus mucosa	UBERON:0002469	44.65	silver quality
skin of leg	UBERON:0001511	44.49	gold quality
right hemisphere of cerebellum	UBERON:0014890	43.73	silver quality
hypothalamus	UBERON:0001898	43.71	gold quality
omental fat pad	UBERON:0010414	43.28	silver quality
frontal cortex	UBERON:0001870	43.26	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	41.84	silver quality
left lobe of thyroid gland	UBERON:0001120	41.47	silver quality
skin of abdomen	UBERON:0001416	41.39	silver quality
thyroid gland	UBERON:0002046	41.26	silver quality
anterior cingulate cortex	UBERON:0009835	40.85	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.98

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC02190 inhibits the embryo-endometrial attachment by decreasing ITGAD expression. (PMID:35038314)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.