LINC02191

Summary

LINC02191 (long intergenic non-protein coding RNA 2191, HGNC:53053) is a long non-coding RNA gene on chromosome 16p12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53053
Approved symbol	LINC02191
Name	long intergenic non-protein coding RNA 2191
Location	16p12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261636
Ensembl biotype	lncRNA
Entrez	105371146
RNAcentral	URS0000EF459D — lncRNA, 1458 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000568036, ENST00000718517

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000568036 — 4 exons

Exon	Start	End
ENSE00002594447	25419812	25420160
ENSE00002604166	25423999	25424264
ENSE00003851378	25431336	25431531
ENSE00003881419	25433040	25433686

Expression profiles

Bgee: expression breadth tissue_specific, 10 present calls, max score 54.49.

Top tissues by expression

10 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
monocyte	CL:0000576	54.49	gold quality
putamen	UBERON:0001874	51.75	gold quality
left testis	UBERON:0004533	49.18	gold quality
testis	UBERON:0000473	48.55	gold quality
islet of Langerhans	UBERON:0000006	47.93	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	45.97	silver quality
right testis	UBERON:0004534	45.33	gold quality
gastrocnemius	UBERON:0001388	40.83	gold quality
tibial artery	UBERON:0007610	37.66	silver quality
skin of leg	UBERON:0001511	34.61	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.30

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Exosomal lncRNA LINC02191 Promotes Laryngeal Squamous cell Carcinoma Progression by Targeting miR-204-5p/RAB22A Axis and Regulating PI3K/Akt/mTOR Pathway. (PMID:37863866)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.