LINC02208

Summary

LINC02208 (long intergenic non-protein coding RNA 2208, HGNC:52978) is a long non-coding RNA gene on chromosome 5q23.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52978
Approved symbol	LINC02208
Name	long intergenic non-protein coding RNA 2208
Location	5q23.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	HRAT56
Ensembl gene	ENSG00000250891
Ensembl biotype	lncRNA
Entrez	101927280
RNAcentral	URS000075AE83 — lncRNA, 3199 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 24 — 24 lncRNA

ENST00000506769, ENST00000515704, ENST00000653787, ENST00000654806, ENST00000655008, ENST00000659234, ENST00000659881, ENST00000660173, ENST00000660915, ENST00000661194, ENST00000661749, ENST00000662796, ENST00000665746, ENST00000666092, ENST00000667817, ENST00000736426, ENST00000736427, ENST00000736428, ENST00000736429, ENST00000736430, ENST00000736431, ENST00000736432, ENST00000736433, ENST00000736434

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000506769 — 9 exons

Exon	Start	End
ENSE00002028958	118474372	118474427
ENSE00002031426	118472063	118472189
ENSE00002043161	118468156	118468434
ENSE00002047774	118523649	118523814
ENSE00002053601	118472849	118472906
ENSE00002074524	118521172	118522846
ENSE00002076411	118469081	118469148
ENSE00004069766	118510888	118511064
ENSE00004069776	118561921	118562118

Expression profiles

Bgee: expression breadth ubiquitous, 114 present calls, max score 87.41.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0402 / max 22.1236, expressed in 9 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
63064	0.0402	9

Top tissues by expression

114 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right atrium auricular region	UBERON:0006631	87.41	gold quality
apex of heart	UBERON:0002098	86.22	gold quality
heart left ventricle	UBERON:0002084	83.86	gold quality
heart	UBERON:0000948	83.34	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.50	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	73.50	gold quality
colonic epithelium	UBERON:0000397	73.07	silver quality
skeletal muscle tissue	UBERON:0001134	56.27	gold quality
tonsil	UBERON:0002372	54.88	gold quality
hindlimb stylopod muscle	UBERON:0004252	54.05	silver quality
leukocyte	CL:0000738	53.55	gold quality
monocyte	CL:0000576	52.82	gold quality
blood	UBERON:0000178	52.49	gold quality
thyroid gland	UBERON:0002046	52.41	gold quality
left lobe of thyroid gland	UBERON:0001120	51.95	gold quality
right lobe of thyroid gland	UBERON:0001119	51.70	gold quality
mucosa of stomach	UBERON:0001199	51.67	gold quality
prefrontal cortex	UBERON:0000451	51.03	gold quality
primary visual cortex	UBERON:0002436	50.92	gold quality
gall bladder	UBERON:0002110	50.69	gold quality
endometrium	UBERON:0001295	50.01	gold quality
lymph node	UBERON:0000029	49.81	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	49.61	gold quality
islet of Langerhans	UBERON:0000006	49.45	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.25	gold quality
calcaneal tendon	UBERON:0003701	49.21	silver quality
adult mammalian kidney	UBERON:0000082	49.14	gold quality
uterine cervix	UBERON:0000002	48.92	gold quality
kidney	UBERON:0002113	48.37	gold quality
smooth muscle tissue	UBERON:0001135	48.28	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.91

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.