LINC02216

Summary

LINC02216 (long intergenic non-protein coding RNA 2216, HGNC:53083) is a long non-coding RNA gene on chromosome 5q23.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53083
Approved symbol	LINC02216
Name	long intergenic non-protein coding RNA 2216
Location	5q23.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249551
Ensembl biotype	lncRNA
Entrez	105379141
RNAcentral	URS00026A2715 — lncRNA, 742 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000513366, ENST00000830570

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000513366 — 5 exons

Exon	Start	End
ENSE00002038998	118579654	118579794
ENSE00002047218	118581269	118581324
ENSE00002047319	118580532	118580648
ENSE00002059664	118575575	118575686
ENSE00002066092	118577040	118577194

Expression profiles

Bgee: expression breadth broad, 95 present calls, max score 83.27.

Top tissues by expression

95 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.27	silver quality
ganglionic eminence	UBERON:0004023	62.71	gold quality
cortical plate	UBERON:0005343	62.50	gold quality
monocyte	CL:0000576	56.13	gold quality
islet of Langerhans	UBERON:0000006	55.95	gold quality
sural nerve	UBERON:0015488	55.68	silver quality
liver	UBERON:0002107	53.92	silver quality
stromal cell of endometrium	CL:0002255	53.66	silver quality
prefrontal cortex	UBERON:0000451	53.27	gold quality
blood	UBERON:0000178	51.95	gold quality
calcaneal tendon	UBERON:0003701	51.90	silver quality
bone marrow	UBERON:0002371	51.58	silver quality
lymph node	UBERON:0000029	51.55	gold quality
primary visual cortex	UBERON:0002436	50.97	gold quality
smooth muscle tissue	UBERON:0001135	50.79	gold quality
tonsil	UBERON:0002372	49.16	gold quality
cortex of kidney	UBERON:0001225	47.62	silver quality
endometrium	UBERON:0001295	47.53	gold quality
muscle of leg	UBERON:0001383	47.32	gold quality
pancreas	UBERON:0001264	46.97	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	46.86	silver quality
right lobe of liver	UBERON:0001114	46.14	silver quality
adult mammalian kidney	UBERON:0000082	45.83	silver quality
gastrocnemius	UBERON:0001388	45.80	gold quality
fallopian tube	UBERON:0003889	45.76	gold quality
adenohypophysis	UBERON:0002196	45.34	gold quality
heart left ventricle	UBERON:0002084	45.01	silver quality
cerebellar cortex	UBERON:0002129	44.54	silver quality
cerebral cortex	UBERON:0000956	44.03	gold quality
saliva-secreting gland	UBERON:0001044	43.99	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.76

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.