LINC02222

Summary

LINC02222 (long intergenic non-protein coding RNA 2222, HGNC:53091) is a long non-coding RNA gene on chromosome 5q35.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53091
Approved symbol	LINC02222
Name	long intergenic non-protein coding RNA 2222
Location	5q35.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248717
Ensembl biotype	lncRNA
Entrez	105377765
RNAcentral	URS0000BC4482 — lncRNA, 1720 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000513535, ENST00000703627

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000513535 — 2 exons

Exon	Start	End
ENSE00002038277	180685649	180687502
ENSE00002044294	180683724	180684906

Expression profiles

Bgee: expression breadth broad, 84 present calls, max score 90.11.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0043 / max 4.5108, expressed in 2 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
203819	0.0043	2

Top tissues by expression

84 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	90.11	gold quality
testis	UBERON:0000473	66.44	gold quality
left testis	UBERON:0004533	65.98	gold quality
right testis	UBERON:0004534	65.91	gold quality
left ovary	UBERON:0002119	62.35	gold quality
ovary	UBERON:0000992	61.61	gold quality
right ovary	UBERON:0002118	60.86	gold quality
bone marrow	UBERON:0002371	57.27	gold quality
duodenum	UBERON:0002114	55.74	gold quality
lymph node	UBERON:0000029	53.43	gold quality
blood	UBERON:0000178	51.58	silver quality
right uterine tube	UBERON:0001302	51.46	gold quality
multicellular organism	UBERON:0000468	51.21	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	50.41	gold quality
mucosa of stomach	UBERON:0001199	48.60	gold quality
vagina	UBERON:0000996	48.56	gold quality
adrenal tissue	UBERON:0018303	48.04	silver quality
body of stomach	UBERON:0001161	47.86	gold quality
stomach	UBERON:0000945	47.82	gold quality
adult mammalian kidney	UBERON:0000082	47.52	silver quality
muscle of leg	UBERON:0001383	46.92	silver quality
liver	UBERON:0002107	46.67	silver quality
endometrium	UBERON:0001295	46.65	silver quality
right adrenal gland cortex	UBERON:0035827	46.40	gold quality
prefrontal cortex	UBERON:0000451	46.07	silver quality
gastrocnemius	UBERON:0001388	45.97	silver quality
islet of Langerhans	UBERON:0000006	45.92	silver quality
adrenal gland	UBERON:0002369	45.66	gold quality
small intestine	UBERON:0002108	45.65	gold quality
right adrenal gland	UBERON:0001233	45.59	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.80

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.