LINC02226

Summary

LINC02226 (long intergenic non-protein coding RNA 2226, HGNC:53095) is a long non-coding RNA gene on chromosome 5p15.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53095
Approved symbol	LINC02226
Name	long intergenic non-protein coding RNA 2226
Location	5p15.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000245729
Ensembl biotype	lncRNA
Entrez	729506
RNAcentral	URS000075AA19 — lncRNA, 1591 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 21 — 21 lncRNA

ENST00000501071, ENST00000512406, ENST00000607662, ENST00000607691, ENST00000654773, ENST00000847314, ENST00000847315, ENST00000847316, ENST00000847317, ENST00000847318, ENST00000847319, ENST00000847320, ENST00000847321, ENST00000847322, ENST00000847323, ENST00000847324, ENST00000847486, ENST00000847487, ENST00000847488, ENST00000847680, ENST00000847681

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000501071 — 6 exons

Exon	Start	End
ENSE00001963822	8334578	8334726
ENSE00001964231	8457449	8457558
ENSE00001967138	8333481	8334452
ENSE00001975880	8337181	8337295
ENSE00001991128	8387527	8387709
ENSE00003604209	8452223	8452280

Expression profiles

Bgee: expression breadth broad, 53 present calls, max score 80.18.

Top tissues by expression

176 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.18	gold quality
buccal mucosa cell	CL:0002336	61.34	gold quality
ventricular zone	UBERON:0003053	60.21	gold quality
cortical plate	UBERON:0005343	59.68	gold quality
endothelial cell	CL:0000115	59.23	gold quality
ganglionic eminence	UBERON:0004023	58.98	silver quality
tendon of biceps brachii	UBERON:0008188	56.05	gold quality
cartilage tissue	UBERON:0002418	54.78	gold quality
skin of hip	UBERON:0001554	53.37	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	52.95	gold quality
tendon	UBERON:0000043	52.42	gold quality
spinal cord	UBERON:0002240	52.03	gold quality
prefrontal cortex	UBERON:0000451	51.02	gold quality
monocyte	CL:0000576	48.57	silver quality
upper leg skin	UBERON:0004262	48.41	silver quality
islet of Langerhans	UBERON:0000006	48.18	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	48.10	gold quality
sperm	CL:0000019	48.04	gold quality
superior surface of tongue	UBERON:0007371	46.76	gold quality
pancreas	UBERON:0001264	46.62	gold quality
substantia nigra	UBERON:0002038	46.48	gold quality
muscle of leg	UBERON:0001383	46.27	silver quality
midbrain	UBERON:0001891	45.80	gold quality
Brodmann (1909) area 9	UBERON:0013540	45.04	gold quality
body of pancreas	UBERON:0001150	44.82	silver quality
gall bladder	UBERON:0002110	44.47	silver quality
oviduct epithelium	UBERON:0004804	44.47	silver quality
frontal cortex	UBERON:0001870	44.31	gold quality
pituitary gland	UBERON:0000007	44.15	gold quality
neocortex	UBERON:0001950	44.02	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.