LINC02231

Summary

LINC02231 (long intergenic non-protein coding RNA 2231, HGNC:53100) is a long non-coding RNA gene on chromosome 12q14.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53100
Approved symbol	LINC02231
Name	long intergenic non-protein coding RNA 2231
Location	12q14.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-766N7.4
Ensembl gene	ENSG00000248995
Ensembl biotype	lncRNA
Entrez	109729131
RNAcentral	URS0000BC4497 — lncRNA, 460 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000510459, ENST00000730165, ENST00000730166, ENST00000730167, ENST00000730168, ENST00000730169, ENST00000730170, ENST00000730171, ENST00000730172, ENST00000730173

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000510459 — 3 exons

Exon	Start	End
ENSE00002206844	64920845	64921070
ENSE00002219737	64957754	64957857
ENSE00002231964	64982408	64982524

Expression profiles

Bgee: expression breadth broad, 80 present calls, max score 67.88.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0260 / max 16.0302, expressed in 12 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
131872	0.0260	12

Top tissues by expression

80 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
olfactory segment of nasal mucosa	UBERON:0005386	67.88	gold quality
tonsil	UBERON:0002372	67.26	silver quality
islet of Langerhans	UBERON:0000006	62.66	gold quality
prefrontal cortex	UBERON:0000451	59.37	gold quality
primary visual cortex	UBERON:0002436	58.04	gold quality
urinary bladder	UBERON:0001255	57.95	gold quality
blood	UBERON:0000178	57.34	gold quality
superior frontal gyrus	UBERON:0002661	55.84	gold quality
gastrocnemius	UBERON:0001388	55.82	gold quality
monocyte	CL:0000576	52.27	silver quality
fallopian tube	UBERON:0003889	52.27	gold quality
nucleus accumbens	UBERON:0001882	50.83	gold quality
heart	UBERON:0000948	50.50	gold quality
adenohypophysis	UBERON:0002196	50.46	gold quality
frontal cortex	UBERON:0001870	49.83	gold quality
lung	UBERON:0002048	49.74	gold quality
putamen	UBERON:0001874	49.70	gold quality
caudate nucleus	UBERON:0001873	49.34	gold quality
amygdala	UBERON:0001876	49.07	gold quality
anterior cingulate cortex	UBERON:0009835	48.81	gold quality
tibial artery	UBERON:0007610	48.78	gold quality
body of pancreas	UBERON:0001150	48.53	gold quality
brain	UBERON:0000955	48.17	gold quality
cerebral cortex	UBERON:0000956	48.02	gold quality
Ammon’s horn	UBERON:0001954	47.72	gold quality
heart left ventricle	UBERON:0002084	47.46	gold quality
cerebellar hemisphere	UBERON:0002245	47.21	gold quality
right hemisphere of cerebellum	UBERON:0014890	47.14	gold quality
upper lobe of left lung	UBERON:0008952	46.93	gold quality
multicellular organism	UBERON:0000468	46.25	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.