LINC02237

Summary

LINC02237 (long intergenic non-protein coding RNA 2237, HGNC:53108) is a long non-coding RNA gene on chromosome 8q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53108
Approved symbol	LINC02237
Name	long intergenic non-protein coding RNA 2237
Location	8q23.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-1101K5.1
Ensembl gene	ENSG00000253434
Ensembl biotype	lncRNA
Entrez	105375706
RNAcentral	URS00000E7A69 — lncRNA, 477 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000517308, ENST00000521753, ENST00000521904, ENST00000522390, ENST00000524236, ENST00000650619, ENST00000655458, ENST00000832138

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000517308 — 3 exons

Exon	Start	End
ENSE00002095097	111756510	111756826
ENSE00002125051	111745442	111745607
ENSE00003887593	111741920	111742083

Expression profiles

Bgee: expression breadth ubiquitous, 105 present calls, max score 87.59.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0759 / max 19.4781, expressed in 25 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
90280	0.0759	25

Top tissues by expression

218 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	87.59	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.96	gold quality
adrenal tissue	UBERON:0018303	81.25	gold quality
omental fat pad	UBERON:0010414	67.47	gold quality
peritoneum	UBERON:0002358	67.39	gold quality
subcutaneous adipose tissue	UBERON:0002190	66.52	gold quality
adipose tissue of abdominal region	UBERON:0007808	66.00	gold quality
colonic epithelium	UBERON:0000397	65.93	silver quality
hindlimb stylopod muscle	UBERON:0004252	65.77	gold quality
left testis	UBERON:0004533	65.49	gold quality
testis	UBERON:0000473	64.02	gold quality
right testis	UBERON:0004534	63.50	gold quality
adipose tissue	UBERON:0001013	60.94	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	60.07	gold quality
upper lobe of lung	UBERON:0008948	57.42	silver quality
monocyte	CL:0000576	56.40	gold quality
adrenal gland	UBERON:0002369	55.47	gold quality
right adrenal gland cortex	UBERON:0035827	55.23	gold quality
calcaneal tendon	UBERON:0003701	55.11	gold quality
right adrenal gland	UBERON:0001233	54.58	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
apex of heart	UBERON:0002098	53.63	gold quality
epithelial cell of pancreas	CL:0000083	53.56	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
left adrenal gland	UBERON:0001234	53.21	gold quality
ileal mucosa	UBERON:0000331	53.03	silver quality
sural nerve	UBERON:0015488	52.44	silver quality
islet of Langerhans	UBERON:0000006	52.03	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.70

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.