LINC02240

Summary

LINC02240 (long intergenic non-protein coding RNA 2240, HGNC:53118) is a long non-coding RNA gene on chromosome 5q23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53118
Approved symbol	LINC02240
Name	long intergenic non-protein coding RNA 2240
Location	5q23.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260192
Ensembl biotype	lncRNA
Entrez	101927460
RNAcentral	URS000075C5F7 — lncRNA, 1353 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 47 — 47 lncRNA

ENST00000509456, ENST00000512965, ENST00000564199, ENST00000625219, ENST00000642446, ENST00000642715, ENST00000647105, ENST00000653110, ENST00000655934, ENST00000671535, ENST00000825646, ENST00000825647, ENST00000825648, ENST00000825649, ENST00000825650, ENST00000825651, ENST00000825652, ENST00000825653, ENST00000825654, ENST00000825655, ENST00000825656, ENST00000825657, ENST00000825658, ENST00000825659, ENST00000825660, ENST00000825661, ENST00000825662, ENST00000825663, ENST00000825664, ENST00000825665, ENST00000825666, ENST00000825667, ENST00000825668, ENST00000825669, ENST00000825670, ENST00000825671, ENST00000825672, ENST00000825673, ENST00000825674, ENST00000825675, ENST00000825676, ENST00000825677, ENST00000825678, ENST00000825679, ENST00000825680, ENST00000825681, ENST00000825682

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000509456 — 4 exons

Exon	Start	End
ENSE00002039340	124919947	124920122
ENSE00003828866	124893329	124893563
ENSE00004236087	124921470	124922350
ENSE00004236094	124808887	124809274

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 80.75.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2639 / max 87.7002, expressed in 77 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
58253	0.1210	38
58255	0.1143	33
58252	0.0209	16
58254	0.0077	5

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.75	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.67	gold quality
testis	UBERON:0000473	74.28	gold quality
left testis	UBERON:0004533	74.28	gold quality
right testis	UBERON:0004534	73.64	gold quality
corpus callosum	UBERON:0002336	72.83	gold quality
colonic epithelium	UBERON:0000397	71.23	silver quality
bone marrow cell	CL:0002092	68.90	silver quality
monocyte	CL:0000576	62.84	gold quality
sural nerve	UBERON:0015488	62.14	silver quality
stromal cell of endometrium	CL:0002255	61.76	gold quality
ventricular zone	UBERON:0003053	59.92	gold quality
adipose tissue	UBERON:0001013	59.33	gold quality
omental fat pad	UBERON:0010414	59.22	gold quality
subcutaneous adipose tissue	UBERON:0002190	59.20	gold quality
ganglionic eminence	UBERON:0004023	58.17	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.10	gold quality
lymph node	UBERON:0000029	56.55	gold quality
bone marrow	UBERON:0002371	55.86	gold quality
thoracic mammary gland	UBERON:0005200	55.32	gold quality
tonsil	UBERON:0002372	55.31	gold quality
endometrium	UBERON:0001295	54.35	gold quality
blood	UBERON:0000178	52.55	gold quality
left coronary artery	UBERON:0001626	52.09	gold quality
placenta	UBERON:0001987	52.01	gold quality
skin of abdomen	UBERON:0001416	51.89	gold quality
prefrontal cortex	UBERON:0000451	51.46	gold quality
gall bladder	UBERON:0002110	51.37	gold quality
granulocyte	CL:0000094	51.31	silver quality
cortex of kidney	UBERON:0001225	51.29	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.68

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.