LINC02248

Summary

LINC02248 (long intergenic non-protein coding RNA 2248, HGNC:53147) is a long non-coding RNA gene on chromosome 15q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53147
Approved symbol	LINC02248
Name	long intergenic non-protein coding RNA 2248
Location	15q12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235160
Ensembl biotype	lncRNA
Entrez	107984780
RNAcentral	URS0002A4294D — lncRNA, 2254 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 24 — 24 lncRNA

ENST00000450324, ENST00000451579, ENST00000658140, ENST00000662421, ENST00000670116, ENST00000701365, ENST00000826806, ENST00000826807, ENST00000826808, ENST00000826809, ENST00000826810, ENST00000826811, ENST00000826812, ENST00000826813, ENST00000826814, ENST00000826815, ENST00000826816, ENST00000826817, ENST00000826818, ENST00000826819, ENST00000826820, ENST00000826821, ENST00000826822, ENST00000826823

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000450324 — 2 exons

Exon	Start	End
ENSE00001604431	26446429	26446601
ENSE00001616713	26433374	26433716

Expression profiles

Bgee: expression breadth broad, 52 present calls, max score 87.66.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0559 / max 41.4087, expressed in 12 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
145566	0.0207	6
145565	0.0124	4
145564	0.0100	5
145567	0.0081	4
145568	0.0047	2

Top tissues by expression

52 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right atrium auricular region	UBERON:0006631	87.66	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.35	silver quality
heart	UBERON:0000948	76.78	gold quality
apex of heart	UBERON:0002098	73.26	gold quality
heart left ventricle	UBERON:0002084	70.50	gold quality
skeletal muscle tissue	UBERON:0001134	60.06	gold quality
monocyte	CL:0000576	54.97	gold quality
multicellular organism	UBERON:0000468	53.38	gold quality
muscle of leg	UBERON:0001383	50.52	gold quality
prefrontal cortex	UBERON:0000451	49.43	gold quality
skin of leg	UBERON:0001511	49.14	gold quality
Ammon’s horn	UBERON:0001954	49.06	gold quality
gastrocnemius	UBERON:0001388	48.94	silver quality
blood	UBERON:0000178	48.84	gold quality
zone of skin	UBERON:0000014	48.50	gold quality
superior frontal gyrus	UBERON:0002661	47.78	silver quality
skin of abdomen	UBERON:0001416	47.77	gold quality
left lobe of thyroid gland	UBERON:0001120	46.81	gold quality
omental fat pad	UBERON:0010414	46.39	gold quality
cerebral cortex	UBERON:0000956	46.00	gold quality
islet of Langerhans	UBERON:0000006	45.97	silver quality
anterior cingulate cortex	UBERON:0009835	45.05	gold quality
temporal lobe	UBERON:0001871	44.85	gold quality
amygdala	UBERON:0001876	44.56	gold quality
body of pancreas	UBERON:0001150	43.92	silver quality
frontal cortex	UBERON:0001870	43.68	silver quality
right ovary	UBERON:0002118	42.31	silver quality
body of stomach	UBERON:0001161	42.21	silver quality
putamen	UBERON:0001874	42.08	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	42.06	silver quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-HCAD-30	no	79.38
E-ANND-3	no	2.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.