LINC02250

Summary

LINC02250 (long intergenic non-protein coding RNA 2250, HGNC:53148) is a long non-coding RNA gene on chromosome 15q11.2-q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53148
Approved symbol	LINC02250
Name	long intergenic non-protein coding RNA 2250
Location	15q11.2-q12
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_00023273
Ensembl gene	ENSG00000235731
Ensembl biotype	lncRNA
Entrez	105370737
RNAcentral	URS0000E64BD5 — lncRNA, 1371 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000422117, ENST00000651932, ENST00000655390, ENST00000656957, ENST00000659420, ENST00000660564, ENST00000665366, ENST00000826796, ENST00000826797, ENST00000826798

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000422117 — 4 exons

Exon	Start	End
ENSE00001634768	25484831	25486838
ENSE00001651893	25501085	25501252
ENSE00001705697	25578625	25578791
ENSE00001758010	25508059	25508206

Expression profiles

Bgee: expression breadth broad, 95 present calls, max score 77.41.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0048 / max 4.5108, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
149013	0.0048	3

Top tissues by expression

193 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.41	gold quality
buccal mucosa cell	CL:0002336	68.41	gold quality
bone marrow cell	CL:0002092	67.86	silver quality
left testis	UBERON:0004533	60.75	gold quality
adrenal tissue	UBERON:0018303	60.60	gold quality
sural nerve	UBERON:0015488	60.17	silver quality
calcaneal tendon	UBERON:0003701	59.90	gold quality
testis	UBERON:0000473	59.02	gold quality
right testis	UBERON:0004534	58.82	gold quality
corpus callosum	UBERON:0002336	58.50	gold quality
ventricular zone	UBERON:0003053	58.47	silver quality
hindlimb stylopod muscle	UBERON:0004252	54.49	gold quality
lower lobe of lung	UBERON:0008949	54.34	silver quality
tendon	UBERON:0000043	52.42	gold quality
adrenal gland	UBERON:0002369	52.06	gold quality
monocyte	CL:0000576	51.90	gold quality
tonsil	UBERON:0002372	50.64	silver quality
muscle of leg	UBERON:0001383	49.97	gold quality
liver	UBERON:0002107	49.78	silver quality
stomach	UBERON:0000945	48.84	gold quality
gall bladder	UBERON:0002110	48.22	gold quality
lung	UBERON:0002048	47.52	gold quality
gastrocnemius	UBERON:0001388	47.49	gold quality
prefrontal cortex	UBERON:0000451	47.46	gold quality
lymph node	UBERON:0000029	47.29	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	46.97	gold quality
kidney	UBERON:0002113	46.74	gold quality
pancreas	UBERON:0001264	46.70	gold quality
adult mammalian kidney	UBERON:0000082	46.37	gold quality
upper lobe of lung	UBERON:0008948	46.17	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.09

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.