LINC02251

Summary

LINC02251 (long intergenic non-protein coding RNA 2251, HGNC:53149) is a long non-coding RNA gene on chromosome 15q26.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53149
Approved symbol	LINC02251
Name	long intergenic non-protein coding RNA 2251
Location	15q26.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258483
Ensembl biotype	lncRNA
Entrez	105371008
RNAcentral	URS0000BC4649 — lncRNA, 2245 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 14 — 14 lncRNA

ENST00000554798, ENST00000649950, ENST00000657981, ENST00000660238, ENST00000661284, ENST00000661923, ENST00000663386, ENST00000671500, ENST00000841544, ENST00000841545, ENST00000841546, ENST00000841547, ENST00000841548, ENST00000841549

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000554798 — 5 exons

Exon	Start	End
ENSE00002476327	98020456	98020688
ENSE00002533240	98021187	98021777
ENSE00003712871	98007044	98007169
ENSE00003716993	98003380	98003460
ENSE00003726106	98003081	98003273

Expression profiles

Bgee: expression breadth broad, 84 present calls, max score 85.66.

Top tissues by expression

84 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.66	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.77	gold quality
mucosa of transverse colon	UBERON:0004991	78.66	gold quality
colonic epithelium	UBERON:0000397	78.10	gold quality
tonsil	UBERON:0002372	63.42	gold quality
duodenum	UBERON:0002114	63.20	gold quality
corpus callosum	UBERON:0002336	59.39	gold quality
transverse colon	UBERON:0001157	58.24	gold quality
small intestine	UBERON:0002108	58.18	gold quality
urinary bladder	UBERON:0001255	58.15	silver quality
small intestine Peyer’s patch	UBERON:0003454	57.63	gold quality
lymph node	UBERON:0000029	57.30	gold quality
ganglionic eminence	UBERON:0004023	56.78	silver quality
intestine	UBERON:0000160	56.57	gold quality
colon	UBERON:0001155	56.25	gold quality
monocyte	CL:0000576	56.01	gold quality
myometrium	UBERON:0001296	55.13	gold quality
prefrontal cortex	UBERON:0000451	55.03	gold quality
vermiform appendix	UBERON:0001154	54.84	gold quality
muscle layer of sigmoid colon	UBERON:0035805	54.39	gold quality
Ammon’s horn	UBERON:0001954	53.30	gold quality
primary visual cortex	UBERON:0002436	52.86	gold quality
Brodmann (1909) area 9	UBERON:0013540	52.51	gold quality
blood	UBERON:0000178	52.15	gold quality
adult mammalian kidney	UBERON:0000082	52.00	gold quality
tibial nerve	UBERON:0001323	51.76	gold quality
frontal cortex	UBERON:0001870	50.54	gold quality
cerebral cortex	UBERON:0000956	50.20	gold quality
substantia nigra	UBERON:0002038	50.06	gold quality
superior frontal gyrus	UBERON:0002661	49.87	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.12

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.