LINC02266

Summary

LINC02266 (long intergenic non-protein coding RNA 2266, HGNC:53180) is a long non-coding RNA gene on chromosome 4q31.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53180
Approved symbol	LINC02266
Name	long intergenic non-protein coding RNA 2266
Location	4q31.21
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-142A22.4
Ensembl gene	ENSG00000272727
Ensembl biotype	lncRNA
Entrez	105377466
RNAcentral	URS0000BC44BF — lncRNA, 1153 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000610239, ENST00000654926, ENST00000659559, ENST00000659879, ENST00000660722, ENST00000664112, ENST00000667468, ENST00000768763, ENST00000768764, ENST00000768765, ENST00000768766, ENST00000768767, ENST00000768768

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000610239 — 4 exons

Exon	Start	End
ENSE00003703259	145335263	145336119
ENSE00003703698	145337201	145337313
ENSE00003706587	145338965	145339084
ENSE00003866404	145340361	145340481

Expression profiles

Bgee: expression breadth broad, 92 present calls, max score 92.11.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0197 / max 4.7547, expressed in 7 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
54231	0.0103	5
54230	0.0093	5

Top tissues by expression

92 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.11	gold quality
colonic epithelium	UBERON:0000397	71.91	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	70.91	gold quality
calcaneal tendon	UBERON:0003701	65.30	gold quality
islet of Langerhans	UBERON:0000006	65.26	gold quality
pancreas	UBERON:0001264	58.38	gold quality
liver	UBERON:0002107	57.30	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.17	silver quality
skeletal muscle tissue	UBERON:0001134	56.45	gold quality
endometrium	UBERON:0001295	56.29	gold quality
right lobe of liver	UBERON:0001114	55.61	gold quality
monocyte	CL:0000576	55.13	gold quality
placenta	UBERON:0001987	53.47	gold quality
smooth muscle tissue	UBERON:0001135	51.74	gold quality
prefrontal cortex	UBERON:0000451	51.49	gold quality
urinary bladder	UBERON:0001255	50.83	gold quality
muscle of leg	UBERON:0001383	50.51	silver quality
lymph node	UBERON:0000029	50.17	silver quality
right adrenal gland cortex	UBERON:0035827	49.70	gold quality
vermiform appendix	UBERON:0001154	49.44	gold quality
adrenal tissue	UBERON:0018303	48.75	silver quality
gastrocnemius	UBERON:0001388	48.07	silver quality
myometrium	UBERON:0001296	47.39	gold quality
thoracic mammary gland	UBERON:0005200	47.25	gold quality
blood	UBERON:0000178	47.20	gold quality
gall bladder	UBERON:0002110	47.20	gold quality
right adrenal gland	UBERON:0001233	47.19	gold quality
body of uterus	UBERON:0009853	46.82	gold quality
adrenal gland	UBERON:0002369	46.61	gold quality
left adrenal gland	UBERON:0001234	46.18	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.