LINC02268

Summary

LINC02268 (long intergenic non-protein coding RNA 2268, HGNC:53183) is a long non-coding RNA gene on chromosome 4q34.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53183
Approved symbol	LINC02268
Name	long intergenic non-protein coding RNA 2268
Location	4q34.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248174
Ensembl biotype	lncRNA
Entrez	101928509
RNAcentral	URS00001E60D9 — lncRNA, 1328 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 40 — 40 lncRNA

ENST00000503140, ENST00000511346, ENST00000515444, ENST00000656529, ENST00000662272, ENST00000666320, ENST00000670219, ENST00000671681, ENST00000687371, ENST00000689349, ENST00000691783, ENST00000701407, ENST00000729418, ENST00000729419, ENST00000729420, ENST00000729421, ENST00000729422, ENST00000729423, ENST00000729424, ENST00000729425, ENST00000729426, ENST00000729427, ENST00000729428, ENST00000729429, ENST00000729430, ENST00000729431, ENST00000729432, ENST00000729433, ENST00000729434, ENST00000729435, ENST00000729436, ENST00000729437, ENST00000729438, ENST00000729439, ENST00000729440, ENST00000729441, ENST00000729442, ENST00000729443, ENST00000729444, ENST00000729716

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000503140 — 7 exons

Exon	Start	End
ENSE00002019156	174119897	174120086
ENSE00002042069	174096732	174096783
ENSE00002055514	174114041	174114272
ENSE00002085846	174097623	174097829
ENSE00004056975	174091730	174093297
ENSE00004056986	174120419	174120571
ENSE00004056994	174095357	174095481

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 85.48.

FANTOM5 (CAGE): breadth broad, TPM avg 0.6377 / max 167.9023, expressed in 224 samples.

FANTOM5 promoters (9 alternative TSS)

Promoter ID	TPM avg	Samples expressed
54893	0.5322	206
54894	0.0273	3
54895	0.0188	6
54888	0.0153	2
54887	0.0131	4
54892	0.0114	1
54890	0.0090	1
54889	0.0074	2
54891	0.0032	1

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.48	gold quality
endometrium	UBERON:0001295	77.10	gold quality
muscle layer of sigmoid colon	UBERON:0035805	76.46	gold quality
lower esophagus muscularis layer	UBERON:0035833	75.81	gold quality
left ovary	UBERON:0002119	75.74	gold quality
lower esophagus	UBERON:0013473	75.71	gold quality
tibial nerve	UBERON:0001323	75.20	gold quality
right ovary	UBERON:0002118	74.99	gold quality
ovary	UBERON:0000992	74.30	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	74.08	gold quality
colonic epithelium	UBERON:0000397	74.05	gold quality
bone marrow cell	CL:0002092	72.46	silver quality
right atrium auricular region	UBERON:0006631	72.00	gold quality
cortical plate	UBERON:0005343	70.44	gold quality
gall bladder	UBERON:0002110	69.48	gold quality
stromal cell of endometrium	CL:0002255	68.91	gold quality
ventricular zone	UBERON:0003053	68.42	gold quality
placenta	UBERON:0001987	67.80	gold quality
sural nerve	UBERON:0015488	67.33	gold quality
colon	UBERON:0001155	67.31	gold quality
urinary bladder	UBERON:0001255	66.12	gold quality
myometrium	UBERON:0001296	65.40	gold quality
fundus of stomach	UBERON:0001160	65.39	gold quality
heart	UBERON:0000948	64.94	gold quality
intestine	UBERON:0000160	64.84	gold quality
omental fat pad	UBERON:0010414	64.61	gold quality
mucosa of stomach	UBERON:0001199	63.73	gold quality
esophagus	UBERON:0001043	63.27	gold quality
left coronary artery	UBERON:0001626	62.96	gold quality
ganglionic eminence	UBERON:0004023	62.77	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.42

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.