LINC02269

Summary

LINC02269 (long intergenic non-protein coding RNA 2269, HGNC:53184) is a long non-coding RNA gene on chromosome 4q34.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53184
Approved symbol	LINC02269
Name	long intergenic non-protein coding RNA 2269
Location	4q34.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250708
Ensembl biotype	lncRNA
Entrez	101928478
RNAcentral	URS0000373903 — lncRNA, 499 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 32 — 32 lncRNA

ENST00000509968, ENST00000512263, ENST00000654188, ENST00000654333, ENST00000654653, ENST00000654916, ENST00000655323, ENST00000656512, ENST00000656853, ENST00000659294, ENST00000659629, ENST00000660497, ENST00000660997, ENST00000661458, ENST00000661951, ENST00000664651, ENST00000664849, ENST00000665324, ENST00000665435, ENST00000665681, ENST00000665923, ENST00000667443, ENST00000667922, ENST00000670652, ENST00000670956, ENST00000781415, ENST00000781416, ENST00000781417, ENST00000781418, ENST00000781419, ENST00000781420, ENST00000781421

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000509968 — 4 exons

Exon	Start	End
ENSE00002036486	173925878	173925957
ENSE00002063348	173928490	173928644
ENSE00003869564	173897241	173897320
ENSE00004153527	173929225	173929522

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 91.65.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0457 / max 12.9448, expressed in 15 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
50641	0.0245	7
50645	0.0174	5
50644	0.0038	3

Top tissues by expression

238 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
descending thoracic aorta	UBERON:0002345	91.65	gold quality
ascending aorta	UBERON:0001496	89.82	gold quality
thoracic aorta	UBERON:0001515	89.80	gold quality
sperm	CL:0000019	87.00	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.25	gold quality
lower esophagus	UBERON:0013473	82.12	gold quality
lower esophagus muscularis layer	UBERON:0035833	82.09	gold quality
heart left ventricle	UBERON:0002084	80.02	gold quality
cardiac ventricle	UBERON:0002082	79.29	gold quality
apex of heart	UBERON:0002098	78.58	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	78.10	gold quality
aorta	UBERON:0000947	76.85	gold quality
esophagus	UBERON:0001043	72.80	gold quality
left testis	UBERON:0004533	72.63	gold quality
heart	UBERON:0000948	72.56	gold quality
left coronary artery	UBERON:0001626	71.78	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	71.62	gold quality
right testis	UBERON:0004534	71.54	gold quality
right coronary artery	UBERON:0001625	70.62	gold quality
left ventricle myocardium	UBERON:0006566	70.39	gold quality
testis	UBERON:0000473	70.06	gold quality
coronary artery	UBERON:0001621	69.98	gold quality
mucosa of stomach	UBERON:0001199	69.57	gold quality
gall bladder	UBERON:0002110	69.00	gold quality
popliteal artery	UBERON:0002250	67.24	gold quality
tibial artery	UBERON:0007610	67.23	gold quality
cardiac muscle of right atrium	UBERON:0003379	64.53	gold quality
muscle layer of sigmoid colon	UBERON:0035805	64.24	gold quality
right atrium auricular region	UBERON:0006631	63.57	gold quality
myocardium	UBERON:0002349	63.54	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-MTAB-11268	yes	737.82
E-ANND-3	no	1.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.