LINC02274

Summary

LINC02274 (long intergenic non-protein coding RNA 2274, HGNC:53190) is a long non-coding RNA gene on chromosome 14q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53190
Approved symbol	LINC02274
Name	long intergenic non-protein coding RNA 2274
Location	14q24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258586
Ensembl biotype	lncRNA
Entrez	100506498
RNAcentral	URS0000A7782C — lncRNA, 1202 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000555539

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000555539 — 2 exons

Exon	Start	End
ENSE00002461163	73829896	73830135
ENSE00002463077	73822559	73823492

Expression profiles

Bgee: expression breadth ubiquitous, 138 present calls, max score 84.18.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0796 / max 25.0158, expressed in 23 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
143998	0.0701	23
143999	0.0095	3

Top tissues by expression

228 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	84.18	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.11	silver quality
metanephros cortex	UBERON:0010533	77.75	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.62	silver quality
adult mammalian kidney	UBERON:0000082	71.29	gold quality
kidney	UBERON:0002113	67.93	gold quality
metanephros	UBERON:0000081	66.74	gold quality
cortex of kidney	UBERON:0001225	66.65	gold quality
hindlimb stylopod muscle	UBERON:0004252	63.12	gold quality
sural nerve	UBERON:0015488	62.76	silver quality
cortical plate	UBERON:0005343	60.41	gold quality
lower esophagus mucosa	UBERON:0035834	58.29	gold quality
ganglionic eminence	UBERON:0004023	56.80	gold quality
vermiform appendix	UBERON:0001154	54.68	gold quality
calcaneal tendon	UBERON:0003701	53.70	gold quality
monocyte	CL:0000576	53.60	gold quality
right lobe of liver	UBERON:0001114	51.44	gold quality
muscle of leg	UBERON:0001383	51.17	gold quality
islet of Langerhans	UBERON:0000006	51.10	gold quality
renal medulla	UBERON:0000362	51.02	gold quality
endometrium	UBERON:0001295	50.82	gold quality
gastrocnemius	UBERON:0001388	50.70	gold quality
left ovary	UBERON:0002119	50.48	gold quality
right adrenal gland cortex	UBERON:0035827	50.40	gold quality
adrenal tissue	UBERON:0018303	50.24	gold quality
prefrontal cortex	UBERON:0000451	50.00	gold quality
right ovary	UBERON:0002118	49.73	gold quality
adrenal gland	UBERON:0002369	49.61	gold quality
left adrenal gland cortex	UBERON:0035825	49.60	gold quality
pancreas	UBERON:0001264	48.95	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.