LINC02277

Summary

LINC02277 (long intergenic non-protein coding RNA 2277, HGNC:53193) is a long non-coding RNA gene on chromosome 14q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53193
Approved symbol	LINC02277
Name	long intergenic non-protein coding RNA 2277
Location	14q21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258487
Ensembl biotype	lncRNA
Entrez	107984027
RNAcentral	URS0002A3A424 — lncRNA, 993 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 26 — 26 lncRNA

ENST00000553386, ENST00000556472, ENST00000557506, ENST00000557721, ENST00000653326, ENST00000716793, ENST00000716794, ENST00000716795, ENST00000795526, ENST00000795527, ENST00000795528, ENST00000795529, ENST00000795530, ENST00000795531, ENST00000795532, ENST00000795533, ENST00000795534, ENST00000795535, ENST00000795536, ENST00000795537, ENST00000795538, ENST00000795539, ENST00000795540, ENST00000795541, ENST00000795542, ENST00000795543

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000553386 — 3 exons

Exon	Start	End
ENSE00002489125	44478720	44478851
ENSE00004180329	44466935	44467169
ENSE00004180342	44480510	44480643

Expression profiles

Bgee: expression breadth broad, 89 present calls, max score 88.94.

Top tissues by expression

89 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.94	gold quality
right testis	UBERON:0004534	68.13	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.05	gold quality
left testis	UBERON:0004533	67.42	gold quality
testis	UBERON:0000473	67.20	gold quality
sural nerve	UBERON:0015488	67.10	silver quality
calcaneal tendon	UBERON:0003701	62.27	gold quality
monocyte	CL:0000576	59.45	gold quality
islet of Langerhans	UBERON:0000006	58.00	gold quality
cortex of kidney	UBERON:0001225	57.98	gold quality
tonsil	UBERON:0002372	56.94	silver quality
endometrium	UBERON:0001295	54.51	silver quality
blood	UBERON:0000178	53.99	gold quality
right lobe of liver	UBERON:0001114	53.86	gold quality
placenta	UBERON:0001987	52.62	gold quality
prefrontal cortex	UBERON:0000451	52.22	gold quality
adrenal tissue	UBERON:0018303	50.53	gold quality
myometrium	UBERON:0001296	50.41	gold quality
multicellular organism	UBERON:0000468	48.77	gold quality
urinary bladder	UBERON:0001255	48.56	gold quality
thyroid gland	UBERON:0002046	48.34	gold quality
kidney	UBERON:0002113	47.61	gold quality
smooth muscle tissue	UBERON:0001135	47.30	gold quality
left lobe of thyroid gland	UBERON:0001120	47.07	gold quality
body of pancreas	UBERON:0001150	46.91	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	46.74	gold quality
tibial artery	UBERON:0007610	46.42	gold quality
ascending aorta	UBERON:0001496	46.36	gold quality
corpus callosum	UBERON:0002336	46.16	silver quality
prostate gland	UBERON:0002367	46.16	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.95

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.