LINC02278

Summary

LINC02278 (long intergenic non-protein coding RNA 2278, HGNC:53194) is a long non-coding RNA gene on chromosome 4p14.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53194
Approved symbol	LINC02278
Name	long intergenic non-protein coding RNA 2278
Location	4p14
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251635
Ensembl biotype	lncRNA
Entrez	105374411
RNAcentral	URS0000BC43CB — lncRNA, 3789 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000512170, ENST00000653380, ENST00000807567, ENST00000807568

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000512170 — 3 exons

Exon	Start	End
ENSE00002028333	38569087	38569252
ENSE00004201774	38570452	38571288
ENSE00004201776	38564003	38564116

Expression profiles

Bgee: expression breadth broad, 80 present calls, max score 87.94.

Top tissues by expression

80 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.94	gold quality
cortical plate	UBERON:0005343	56.59	silver quality
prefrontal cortex	UBERON:0000451	54.71	gold quality
primary visual cortex	UBERON:0002436	54.32	gold quality
myometrium	UBERON:0001296	54.29	silver quality
liver	UBERON:0002107	52.77	silver quality
corpus callosum	UBERON:0002336	52.64	gold quality
islet of Langerhans	UBERON:0000006	52.54	gold quality
vermiform appendix	UBERON:0001154	52.54	gold quality
monocyte	CL:0000576	50.95	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	50.77	gold quality
frontal cortex	UBERON:0001870	50.66	gold quality
cortex of kidney	UBERON:0001225	50.23	silver quality
urinary bladder	UBERON:0001255	50.09	silver quality
blood	UBERON:0000178	50.06	silver quality
substantia nigra	UBERON:0002038	50.04	gold quality
amygdala	UBERON:0001876	49.69	gold quality
calcaneal tendon	UBERON:0003701	49.53	silver quality
putamen	UBERON:0001874	48.82	gold quality
Ammon’s horn	UBERON:0001954	48.82	gold quality
superior frontal gyrus	UBERON:0002661	48.79	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	48.59	gold quality
cerebral cortex	UBERON:0000956	48.13	gold quality
brain	UBERON:0000955	47.70	gold quality
lower esophagus muscularis layer	UBERON:0035833	47.58	gold quality
thoracic aorta	UBERON:0001515	47.22	gold quality
gall bladder	UBERON:0002110	47.12	gold quality
Brodmann (1909) area 9	UBERON:0013540	47.08	gold quality
adrenal gland	UBERON:0002369	46.68	gold quality
left coronary artery	UBERON:0001626	46.46	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.96

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.