LINC02281

Summary

LINC02281 (long intergenic non-protein coding RNA 2281, HGNC:53197) is a long non-coding RNA gene on chromosome 14q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53197
Approved symbol	LINC02281
Name	long intergenic non-protein coding RNA 2281
Location	14q12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000257748
Ensembl biotype	lncRNA
Entrez	105370423
RNAcentral	URS0000EEBDAA — lncRNA, 376 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000549013, ENST00000653605, ENST00000787271, ENST00000787272, ENST00000787273, ENST00000787274, ENST00000787275, ENST00000787276, ENST00000787277, ENST00000787278, ENST00000787279, ENST00000787280

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000549013 — 4 exons

Exon	Start	End
ENSE00002334561	28830126	28830204
ENSE00002352213	28824856	28824947
ENSE00002357003	28819600	28819677
ENSE00002390736	28800084	28800209

Expression profiles

Bgee: expression breadth broad, 79 present calls, max score 87.67.

Top tissues by expression

79 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.67	gold quality
right testis	UBERON:0004534	73.89	gold quality
testis	UBERON:0000473	73.58	gold quality
left testis	UBERON:0004533	73.19	gold quality
ganglionic eminence	UBERON:0004023	72.19	gold quality
cortical plate	UBERON:0005343	70.62	gold quality
caudate nucleus	UBERON:0001873	61.37	gold quality
putamen	UBERON:0001874	60.72	gold quality
corpus callosum	UBERON:0002336	60.05	gold quality
vermiform appendix	UBERON:0001154	58.87	gold quality
nucleus accumbens	UBERON:0001882	58.41	gold quality
prefrontal cortex	UBERON:0000451	56.30	gold quality
multicellular organism	UBERON:0000468	56.18	gold quality
calcaneal tendon	UBERON:0003701	56.06	gold quality
monocyte	CL:0000576	55.07	gold quality
bone marrow	UBERON:0002371	54.62	silver quality
brain	UBERON:0000955	54.37	gold quality
primary visual cortex	UBERON:0002436	54.17	gold quality
myometrium	UBERON:0001296	52.93	gold quality
Brodmann (1909) area 9	UBERON:0013540	52.72	gold quality
liver	UBERON:0002107	52.70	gold quality
substantia nigra	UBERON:0002038	52.31	gold quality
blood	UBERON:0000178	52.28	gold quality
muscle of leg	UBERON:0001383	51.83	gold quality
Ammon’s horn	UBERON:0001954	51.58	gold quality
heart left ventricle	UBERON:0002084	51.30	gold quality
tonsil	UBERON:0002372	51.13	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	50.98	gold quality
gastrocnemius	UBERON:0001388	50.85	gold quality
cerebral cortex	UBERON:0000956	50.35	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.14

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.