LINC02289

Summary

LINC02289 (long intergenic non-protein coding RNA 2289, HGNC:53205) is a long non-coding RNA gene on chromosome 14q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53205
Approved symbol	LINC02289
Name	long intergenic non-protein coding RNA 2289
Location	14q24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258819
Ensembl biotype	lncRNA
Entrez	102724190
RNAcentral	URS000027972B — lncRNA, 1817 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000554043, ENST00000555512, ENST00000556781, ENST00000557526, ENST00000658895, ENST00000660008, ENST00000660156, ENST00000660476, ENST00000716887, ENST00000716888, ENST00000716889, ENST00000716890, ENST00000716891, ENST00000716908, ENST00000716909, ENST00000716910

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000554043 — 3 exons

Exon	Start	End
ENSE00002451520	77086367	77086457
ENSE00002467482	77081362	77081500
ENSE00002483703	77048172	77048421

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 82.93.

FANTOM5 (CAGE): breadth broad, TPM avg 0.5420 / max 113.8682, expressed in 200 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
144207	0.5420	200

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right lung	UBERON:0002167	82.93	gold quality
blood	UBERON:0000178	82.17	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.47	gold quality
omental fat pad	UBERON:0010414	77.96	gold quality
adipose tissue	UBERON:0001013	77.54	gold quality
right uterine tube	UBERON:0001302	77.15	gold quality
subcutaneous adipose tissue	UBERON:0002190	77.15	gold quality
thoracic mammary gland	UBERON:0005200	74.68	gold quality
left uterine tube	UBERON:0001303	73.74	gold quality
upper lobe of left lung	UBERON:0008952	73.39	gold quality
placenta	UBERON:0001987	72.42	gold quality
tibial nerve	UBERON:0001323	72.05	gold quality
right lobe of thyroid gland	UBERON:0001119	72.04	gold quality
endocervix	UBERON:0000458	71.66	gold quality
heart left ventricle	UBERON:0002084	71.52	gold quality
lung	UBERON:0002048	71.47	gold quality
liver	UBERON:0002107	71.22	gold quality
skeletal muscle tissue	UBERON:0001134	71.21	gold quality
spleen	UBERON:0002106	70.56	gold quality
gastrocnemius	UBERON:0001388	70.21	gold quality
colonic epithelium	UBERON:0000397	70.00	silver quality
fallopian tube	UBERON:0003889	69.99	gold quality
left lobe of thyroid gland	UBERON:0001120	69.91	gold quality
heart	UBERON:0000948	69.81	gold quality
stromal cell of endometrium	CL:0002255	69.76	gold quality
right atrium auricular region	UBERON:0006631	69.71	gold quality
muscle tissue	UBERON:0002385	69.60	gold quality
muscle of leg	UBERON:0001383	69.55	gold quality
uterine cervix	UBERON:0000002	69.50	gold quality
thyroid gland	UBERON:0002046	69.49	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.80

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.