LINC02291

Summary

LINC02291 (long intergenic non-protein coding RNA 2291, HGNC:53207) is a long non-coding RNA gene on chromosome 14q32.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53207
Approved symbol	LINC02291
Name	long intergenic non-protein coding RNA 2291
Location	14q32.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000197176
Ensembl biotype	lncRNA
Entrez	100129345
RNAcentral	URS000075DD0F — lncRNA, 1682 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 31 — 31 lncRNA

ENST00000355909, ENST00000554197, ENST00000556163, ENST00000730251, ENST00000730252, ENST00000730253, ENST00000730254, ENST00000730255, ENST00000730256, ENST00000730257, ENST00000730258, ENST00000730259, ENST00000730260, ENST00000730261, ENST00000730262, ENST00000730263, ENST00000730264, ENST00000730265, ENST00000730266, ENST00000730267, ENST00000730268, ENST00000730269, ENST00000730270, ENST00000730271, ENST00000730272, ENST00000730273, ENST00000730274, ENST00000730275, ENST00000730276, ENST00000730277, ENST00000730278

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000355909 — 4 exons

Exon	Start	End
ENSE00001433878	97646162	97646372
ENSE00001533766	97673329	97673442
ENSE00004058649	97632275	97633691
ENSE00004058668	97686359	97686776

Expression profiles

Bgee: expression breadth broad, 38 present calls, max score 68.73.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0502 / max 42.3561, expressed in 3 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
144823	0.0328	3
144822	0.0174	3

Top tissues by expression

48 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
placenta	UBERON:0001987	68.73	gold quality
quadriceps femoris	UBERON:0001377	61.63	gold quality
prostate gland	UBERON:0002367	61.20	gold quality
bone marrow	UBERON:0002371	59.38	silver quality
liver	UBERON:0002107	58.79	silver quality
cerebellar vermis	UBERON:0004720	58.50	gold quality
heart	UBERON:0000948	58.17	silver quality
thymus	UBERON:0002370	57.72	silver quality
skeletal muscle tissue	UBERON:0001134	57.44	silver quality
cortical plate	UBERON:0005343	57.43	gold quality
kidney	UBERON:0002113	57.02	silver quality
spleen	UBERON:0002106	56.85	silver quality
pancreas	UBERON:0001264	56.68	silver quality
caudate nucleus	UBERON:0001873	56.64	silver quality
spinal cord	UBERON:0002240	55.94	silver quality
anterior cingulate cortex	UBERON:0009835	54.03	gold quality
hindlimb stylopod muscle	UBERON:0004252	52.69	silver quality
monocyte	CL:0000576	51.99	gold quality
blood	UBERON:0000178	51.87	silver quality
frontal cortex	UBERON:0001870	51.80	gold quality
vermiform appendix	UBERON:0001154	50.32	gold quality
prefrontal cortex	UBERON:0000451	49.99	gold quality
body of stomach	UBERON:0001161	49.63	gold quality
lymph node	UBERON:0000029	48.85	gold quality
upper lobe of left lung	UBERON:0008952	47.82	gold quality
brain	UBERON:0000955	47.09	silver quality
tonsil	UBERON:0002372	44.80	gold quality
skin of leg	UBERON:0001511	44.57	gold quality
stomach	UBERON:0000945	44.52	gold quality
zone of skin	UBERON:0000014	44.27	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.