LINC02297

Summary

LINC02297 (long intergenic non-protein coding RNA 2297, HGNC:53214) is a long non-coding RNA gene on chromosome 14q11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53214
Approved symbol	LINC02297
Name	long intergenic non-protein coding RNA 2297
Location	14q11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000257504
Ensembl biotype	lncRNA
Entrez	642426
RNAcentral	URS000075C8C7 — lncRNA, 1275 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000548050

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000548050 — 3 exons

Exon	Start	End
ENSE00002380317	18630318	18631531
ENSE00002403771	18633465	18633634
ENSE00002427471	18633096	18633204

Expression profiles

Bgee: expression breadth broad, 32 present calls, max score 78.88.

Top tissues by expression

32 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.88	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	70.08	gold quality
prostate gland	UBERON:0002367	54.18	gold quality
monocyte	CL:0000576	51.85	silver quality
blood	UBERON:0000178	50.57	silver quality
lymph node	UBERON:0000029	49.59	silver quality
calcaneal tendon	UBERON:0003701	49.44	silver quality
tonsil	UBERON:0002372	48.40	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	46.79	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	45.43	gold quality
substantia nigra	UBERON:0002038	44.41	silver quality
subcutaneous adipose tissue	UBERON:0002190	44.07	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	43.94	silver quality
stomach	UBERON:0000945	43.70	silver quality
tibial nerve	UBERON:0001323	43.55	gold quality
putamen	UBERON:0001874	43.46	gold quality
upper lobe of left lung	UBERON:0008952	42.56	silver quality
heart	UBERON:0000948	42.36	silver quality
skin of leg	UBERON:0001511	42.18	gold quality
lower esophagus muscularis layer	UBERON:0035833	41.61	silver quality
right atrium auricular region	UBERON:0006631	41.16	silver quality
body of pancreas	UBERON:0001150	40.44	silver quality
ascending aorta	UBERON:0001496	40.40	silver quality
skin of abdomen	UBERON:0001416	38.87	silver quality
thoracic mammary gland	UBERON:0005200	38.06	silver quality
Ammon’s horn	UBERON:0001954	37.36	silver quality
caudate nucleus	UBERON:0001873	37.11	silver quality
heart left ventricle	UBERON:0002084	36.75	silver quality
vagina	UBERON:0000996	36.43	silver quality
left lobe of thyroid gland	UBERON:0001120	35.83	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.31

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.