LINC02300

Summary

LINC02300 (long intergenic non-protein coding RNA 2300, HGNC:53219) is a long non-coding RNA gene on chromosome 14q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53219
Approved symbol	LINC02300
Name	long intergenic non-protein coding RNA 2300
Location	14q12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258175
Ensembl biotype	lncRNA
Entrez	105370422
RNAcentral	URS0002A2F9D8 — lncRNA, 1347 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000549742, ENST00000757289, ENST00000757290, ENST00000757291

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000549742 — 3 exons

Exon	Start	End
ENSE00002360005	28612322	28612478
ENSE00002376048	28592223	28592565
ENSE00002401779	28613459	28613623

Expression profiles

Bgee: expression breadth broad, 61 present calls, max score 85.67.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0160 / max 11.8608, expressed in 7 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
142695	0.0121	5
142696	0.0039	1

Top tissues by expression

61 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.67	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	77.32	gold quality
minor salivary gland	UBERON:0001830	64.66	gold quality
ganglionic eminence	UBERON:0004023	64.66	gold quality
saliva-secreting gland	UBERON:0001044	64.50	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	57.58	gold quality
rectum	UBERON:0001052	56.93	gold quality
endometrium	UBERON:0001295	56.57	silver quality
blood	UBERON:0000178	53.88	gold quality
thyroid gland	UBERON:0002046	53.46	gold quality
monocyte	CL:0000576	53.41	silver quality
esophagus mucosa	UBERON:0002469	52.72	gold quality
esophagus	UBERON:0001043	52.67	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	51.61	silver quality
multicellular organism	UBERON:0000468	51.57	gold quality
lung	UBERON:0002048	49.97	gold quality
intestine	UBERON:0000160	49.69	gold quality
endocervix	UBERON:0000458	49.18	gold quality
upper lobe of left lung	UBERON:0008952	48.50	gold quality
heart left ventricle	UBERON:0002084	48.02	gold quality
ovary	UBERON:0000992	47.68	silver quality
colon	UBERON:0001155	47.03	gold quality
lower esophagus	UBERON:0013473	46.85	gold quality
muscle layer of sigmoid colon	UBERON:0035805	46.66	gold quality
lower esophagus muscularis layer	UBERON:0035833	45.97	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	45.87	gold quality
fallopian tube	UBERON:0003889	45.80	gold quality
stomach	UBERON:0000945	45.63	gold quality
prostate gland	UBERON:0002367	44.92	gold quality
left adrenal gland cortex	UBERON:0035825	44.80	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.34

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.