LINC02310

Summary

LINC02310 (long intergenic non-protein coding RNA 2310, HGNC:53229) is a long non-coding RNA gene on chromosome 14q22.1.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53229
Approved symbol	LINC02310
Name	long intergenic non-protein coding RNA 2310
Location	14q22.1
Locus type	RNA, long non-coding
Status	Approved
Entrez	105370496
RNAcentral	URS0000BC45F9 — lncRNA, 571 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Identification of LINC02310 as an enhancer in lung adenocarcinoma and investigation of its regulatory network via comprehensive analyses. (PMID:33308216)

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000621974 (14:51397197 G>A), RS1000733486 (14:51391938 A>C,G), RS1000995515 (14:51396967 A>G), RS1001366234 (14:51395084 C>G,T), RS1001500427 (14:51395327 A>G), RS1001797104 (14:51397551 CT>C), RS1001869215 (14:51397723 A>G), RS1001972560 (14:51391873 AACAC>A,AAC), RS1002408280 (14:51393638 T>C), RS1002643382 (14:51394559 G>A), RS1002980183 (14:51394295 A>G), RS1003175751 (14:51396434 C>T), RS1003543643 (14:51398975 C>T), RS1003877575 (14:51391912 A>C), RS1003910153 (14:51392146 A>G)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

CTD chemical–gene interactions

3 total (human), top 3 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
sodium arsenite	increases expression	1
Smoke	decreases expression	1
Cadmium Chloride	increases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.