LINC02321

Summary

LINC02321 (long intergenic non-protein coding RNA 2321, HGNC:53240) is a long non-coding RNA gene on chromosome 14q32.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53240
Approved symbol	LINC02321
Name	long intergenic non-protein coding RNA 2321
Location	14q32.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258884
Ensembl biotype	lncRNA
Entrez	105370623
RNAcentral	URS00026A2892 — lncRNA, 669 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 14 — 14 lncRNA

ENST00000555975, ENST00000659138, ENST00000671606, ENST00000825139, ENST00000825140, ENST00000825141, ENST00000825142, ENST00000825143, ENST00000825144, ENST00000825145, ENST00000825146, ENST00000825147, ENST00000825148, ENST00000825149

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000555975 — 3 exons

Exon	Start	End
ENSE00002479413	90823022	90823153
ENSE00004235172	90827989	90828202
ENSE00004235182	90821270	90822476

Expression profiles

Bgee: expression breadth ubiquitous, 118 present calls, max score 83.17.

FANTOM5 (CAGE): breadth broad, TPM avg 0.4834 / max 24.0420, expressed in 234 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
144473	0.4834	234

Top tissues by expression

118 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.17	gold quality
islet of Langerhans	UBERON:0000006	72.47	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	70.90	gold quality
ganglionic eminence	UBERON:0004023	63.63	gold quality
ventricular zone	UBERON:0003053	63.55	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.71	gold quality
pancreas	UBERON:0001264	61.88	gold quality
liver	UBERON:0002107	59.86	gold quality
right testis	UBERON:0004534	59.31	gold quality
testis	UBERON:0000473	58.57	gold quality
bone marrow	UBERON:0002371	58.22	gold quality
lymph node	UBERON:0000029	58.08	gold quality
left testis	UBERON:0004533	58.01	gold quality
right lobe of liver	UBERON:0001114	57.92	gold quality
skeletal muscle tissue	UBERON:0001134	57.67	gold quality
mucosa of transverse colon	UBERON:0004991	57.52	gold quality
spleen	UBERON:0002106	57.49	gold quality
gall bladder	UBERON:0002110	57.12	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	56.61	gold quality
stromal cell of endometrium	CL:0002255	56.51	gold quality
placenta	UBERON:0001987	55.67	gold quality
right adrenal gland cortex	UBERON:0035827	55.44	gold quality
prefrontal cortex	UBERON:0000451	55.30	gold quality
monocyte	CL:0000576	55.22	gold quality
blood	UBERON:0000178	54.84	gold quality
superior frontal gyrus	UBERON:0002661	54.72	gold quality
muscle of leg	UBERON:0001383	54.51	gold quality
adult mammalian kidney	UBERON:0000082	54.19	gold quality
smooth muscle tissue	UBERON:0001135	53.77	gold quality
body of pancreas	UBERON:0001150	53.41	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.65

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• An angiogenesisrelated lncRNA signature for the prognostic prediction of patients with bladder cancer and LINC02321 promotes bladder cancer progression via the VEGFA signaling pathway. (PMID:36579659)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.