LINC02323

Summary

LINC02323 (long intergenic non-protein coding RNA 2323, HGNC:53242) is a long non-coding RNA gene on chromosome 14q32.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53242
Approved symbol	LINC02323
Name	long intergenic non-protein coding RNA 2323
Location	14q32.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259230
Ensembl biotype	lncRNA
Entrez	105370681
RNAcentral	URS00005B183F — lncRNA, 1603 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 20 — 20 lncRNA

ENST00000559946, ENST00000701178, ENST00000716868, ENST00000716869, ENST00000716870, ENST00000766587, ENST00000766588, ENST00000766589, ENST00000766590, ENST00000766591, ENST00000766592, ENST00000766593, ENST00000766594, ENST00000766595, ENST00000766596, ENST00000766597, ENST00000766598, ENST00000766599, ENST00000766600, ENST00000766601

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000559946 — 3 exons

Exon	Start	End
ENSE00002553940	102554710	102555826
ENSE00002575172	102550346	102550508
ENSE00004030932	102545254	102545576

Expression profiles

Bgee: expression breadth broad, 69 present calls, max score 67.75.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0168 / max 4.2999, expressed in 10 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
141666	0.0168	10

Top tissues by expression

69 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
duodenum	UBERON:0002114	67.75	gold quality
esophagus mucosa	UBERON:0002469	61.93	gold quality
esophagus	UBERON:0001043	60.42	gold quality
small intestine	UBERON:0002108	60.21	gold quality
small intestine Peyer’s patch	UBERON:0003454	59.08	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.15	silver quality
ectocervix	UBERON:0012249	56.60	gold quality
cortex of kidney	UBERON:0001225	56.57	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	55.04	gold quality
minor salivary gland	UBERON:0001830	54.44	gold quality
saliva-secreting gland	UBERON:0001044	54.23	gold quality
intestine	UBERON:0000160	53.23	gold quality
vagina	UBERON:0000996	53.19	gold quality
stromal cell of endometrium	CL:0002255	52.71	silver quality
lower esophagus mucosa	UBERON:0035834	51.77	gold quality
myometrium	UBERON:0001296	51.10	silver quality
vermiform appendix	UBERON:0001154	51.06	gold quality
lymph node	UBERON:0000029	50.81	silver quality
body of pancreas	UBERON:0001150	50.18	gold quality
placenta	UBERON:0001987	49.63	gold quality
monocyte	CL:0000576	49.51	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	48.74	gold quality
colon	UBERON:0001155	48.58	gold quality
blood	UBERON:0000178	48.56	gold quality
mucosa of transverse colon	UBERON:0004991	47.99	gold quality
transverse colon	UBERON:0001157	47.67	gold quality
ovary	UBERON:0000992	47.55	gold quality
endocervix	UBERON:0000458	47.37	gold quality
gall bladder	UBERON:0002110	47.26	silver quality
right uterine tube	UBERON:0001302	47.19	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.28

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• Novel long noncoding RNA LINC02323 promotes cell growth and migration of ovarian cancer via TGF-beta receptor 1 by miR-1343-3p. (PMID:33247856)
• LINC02323 facilitates development of lung squamous cell carcinoma by miRNA sponge and RBP dysregulation and links to poor prognosis. (PMID:36516959)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.