LINC02351

Summary

LINC02351 (long intergenic non-protein coding RNA 2351, HGNC:53273) is a long non-coding RNA gene on chromosome 15q26.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53273
Approved symbol	LINC02351
Name	long intergenic non-protein coding RNA 2351
Location	15q26.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000277987
Ensembl biotype	lncRNA
Entrez	105371011
RNAcentral	URS0000BC44C5 — lncRNA, 1322 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 15 lncRNA

ENST00000614728, ENST00000622210, ENST00000661847, ENST00000668582, ENST00000686546, ENST00000717131, ENST00000717132, ENST00000793408, ENST00000793409, ENST00000793410, ENST00000793411, ENST00000793412, ENST00000793413, ENST00000793414, ENST00000793415

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000614728 — 2 exons

Exon	Start	End
ENSE00003720273	98324273	98324420
ENSE00003741182	98327354	98327494

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 81.96.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2698 / max 77.3854, expressed in 102 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
151733	0.2584	101
151732	0.0114	5

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.96	silver quality
skeletal muscle tissue	UBERON:0001134	70.23	gold quality
left uterine tube	UBERON:0001303	68.44	gold quality
subcutaneous adipose tissue	UBERON:0002190	66.80	gold quality
vagina	UBERON:0000996	66.29	gold quality
ectocervix	UBERON:0012249	65.31	gold quality
uterine cervix	UBERON:0000002	64.42	gold quality
liver	UBERON:0002107	63.57	gold quality
tonsil	UBERON:0002372	63.37	gold quality
fundus of stomach	UBERON:0001160	63.30	gold quality
myometrium	UBERON:0001296	62.74	gold quality
endometrium	UBERON:0001295	62.55	gold quality
adipose tissue	UBERON:0001013	62.22	gold quality
thoracic mammary gland	UBERON:0005200	62.07	gold quality
fallopian tube	UBERON:0003889	61.81	gold quality
endocervix	UBERON:0000458	61.67	gold quality
popliteal artery	UBERON:0002250	61.09	gold quality
tibial artery	UBERON:0007610	61.01	gold quality
body of uterus	UBERON:0009853	60.86	gold quality
right coronary artery	UBERON:0001625	60.75	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	59.58	gold quality
thoracic aorta	UBERON:0001515	59.41	gold quality
ascending aorta	UBERON:0001496	59.31	gold quality
descending thoracic aorta	UBERON:0002345	59.22	gold quality
calcaneal tendon	UBERON:0003701	59.05	gold quality
lower esophagus	UBERON:0013473	58.30	gold quality
lower esophagus muscularis layer	UBERON:0035833	58.26	gold quality
mucosa of stomach	UBERON:0001199	57.96	gold quality
prefrontal cortex	UBERON:0000451	57.13	gold quality
smooth muscle tissue	UBERON:0001135	56.68	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.79

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.