LINC02354

Summary

LINC02354 (long intergenic non-protein coding RNA 2354, HGNC:53276) is a long non-coding RNA gene on chromosome 12q13.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53276
Approved symbol	LINC02354
Name	long intergenic non-protein coding RNA 2354
Location	12q13.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000257488
Ensembl biotype	lncRNA
Entrez	107984503
RNAcentral	URS0000377175 — lncRNA, 582 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000546523, ENST00000548564, ENST00000550684, ENST00000550720, ENST00000550909

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000546523 — 2 exons

Exon	Start	End
ENSE00002349459	47834239	47834554
ENSE00002390589	47829494	47829530

Expression profiles

Bgee: expression breadth broad, 94 present calls, max score 91.42.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0115 / max 9.4553, expressed in 2 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
125233	0.0115	2

Top tissues by expression

94 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.42	gold quality
bone marrow cell	CL:0002092	63.08	silver quality
gall bladder	UBERON:0002110	60.39	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.19	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	57.60	gold quality
islet of Langerhans	UBERON:0000006	57.05	gold quality
monocyte	CL:0000576	56.77	gold quality
bone marrow	UBERON:0002371	56.35	gold quality
tonsil	UBERON:0002372	54.98	gold quality
right lobe of liver	UBERON:0001114	54.79	gold quality
blood	UBERON:0000178	53.82	gold quality
cortex of kidney	UBERON:0001225	52.72	gold quality
skin of abdomen	UBERON:0001416	52.71	gold quality
vermiform appendix	UBERON:0001154	52.58	gold quality
zone of skin	UBERON:0000014	52.32	gold quality
skin of leg	UBERON:0001511	51.94	gold quality
kidney	UBERON:0002113	51.59	gold quality
lymph node	UBERON:0000029	51.08	gold quality
calcaneal tendon	UBERON:0003701	50.68	silver quality
adult mammalian kidney	UBERON:0000082	49.74	gold quality
descending thoracic aorta	UBERON:0002345	49.73	gold quality
left adrenal gland cortex	UBERON:0035825	49.70	gold quality
smooth muscle tissue	UBERON:0001135	49.31	gold quality
left adrenal gland	UBERON:0001234	49.30	gold quality
granulocyte	CL:0000094	49.12	silver quality
gastrocnemius	UBERON:0001388	48.80	gold quality
metanephros cortex	UBERON:0010533	48.59	gold quality
adrenal gland	UBERON:0002369	48.42	gold quality
body of pancreas	UBERON:0001150	48.29	gold quality
endocervix	UBERON:0000458	48.07	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.