LINC02371

Summary

LINC02371 (long intergenic non-protein coding RNA 2371, HGNC:53293) is a long non-coding RNA gene on chromosome 12p13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53293
Approved symbol	LINC02371
Name	long intergenic non-protein coding RNA 2371
Location	12p13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000274659
Ensembl biotype	lncRNA
Entrez	107984539
RNAcentral	URS00026A1B18 — lncRNA, 651 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000613818, ENST00000670289, ENST00000686731, ENST00000701181, ENST00000839535, ENST00000839536, ENST00000839537, ENST00000839538

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000613818 — 3 exons

Exon	Start	End
ENSE00003716356	2742074	2742180
ENSE00003984610	2742505	2745519
ENSE00003984611	2740032	2740201

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 80.13.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0402 / max 4.6553, expressed in 27 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
123442	0.0402	27

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	80.13	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.51	silver quality
primary visual cortex	UBERON:0002436	71.67	gold quality
bone marrow cell	CL:0002092	71.65	silver quality
superior frontal gyrus	UBERON:0002661	68.59	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.19	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	66.95	gold quality
anterior cingulate cortex	UBERON:0009835	66.70	gold quality
right frontal lobe	UBERON:0002810	66.24	gold quality
Brodmann (1909) area 9	UBERON:0013540	66.11	gold quality
cerebellum	UBERON:0002037	66.10	gold quality
cerebellar cortex	UBERON:0002129	66.07	gold quality
cerebellar hemisphere	UBERON:0002245	66.01	gold quality
frontal cortex	UBERON:0001870	66.00	gold quality
right hemisphere of cerebellum	UBERON:0014890	65.94	gold quality
cerebral cortex	UBERON:0000956	65.82	gold quality
prefrontal cortex	UBERON:0000451	65.64	gold quality
substantia nigra	UBERON:0002038	63.94	gold quality
brain	UBERON:0000955	63.83	gold quality
hypothalamus	UBERON:0001898	63.83	gold quality
hindlimb stylopod muscle	UBERON:0004252	63.63	gold quality
cortical plate	UBERON:0005343	63.62	gold quality
Ammon’s horn	UBERON:0001954	62.36	gold quality
skeletal muscle tissue	UBERON:0001134	62.32	gold quality
nucleus accumbens	UBERON:0001882	62.24	gold quality
caudate nucleus	UBERON:0001873	62.02	gold quality
stromal cell of endometrium	CL:0002255	61.96	gold quality
putamen	UBERON:0001874	61.67	gold quality
ventricular zone	UBERON:0003053	60.62	gold quality
temporal lobe	UBERON:0001871	60.07	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.31

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.