LINC02374

Summary

LINC02374 (long intergenic non-protein coding RNA 2374, HGNC:53296) is a long non-coding RNA gene on chromosome 4q35.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53296
Approved symbol	LINC02374
Name	long intergenic non-protein coding RNA 2374
Location	4q35.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249747
Ensembl biotype	lncRNA
Entrez	105377600
RNAcentral	URS0000BC463E — lncRNA, 464 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000503637, ENST00000515222, ENST00000763151, ENST00000763152

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000503637 — 2 exons

Exon	Start	End
ENSE00004118969	187201977	187202142
ENSE00004118978	187202982	187203614

Expression profiles

Bgee: expression breadth broad, 68 present calls, max score 79.45.

Top tissues by expression

68 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.45	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	71.09	gold quality
cortical plate	UBERON:0005343	65.62	gold quality
left testis	UBERON:0004533	60.81	gold quality
testis	UBERON:0000473	60.69	gold quality
right testis	UBERON:0004534	58.42	gold quality
islet of Langerhans	UBERON:0000006	50.67	gold quality
blood	UBERON:0000178	50.26	silver quality
multicellular organism	UBERON:0000468	47.91	gold quality
right coronary artery	UBERON:0001625	47.88	gold quality
gastrocnemius	UBERON:0001388	47.57	gold quality
prefrontal cortex	UBERON:0000451	47.31	gold quality
right lobe of liver	UBERON:0001114	45.50	silver quality
ectocervix	UBERON:0012249	45.32	silver quality
upper lobe of left lung	UBERON:0008952	45.25	silver quality
smooth muscle tissue	UBERON:0001135	44.81	gold quality
heart left ventricle	UBERON:0002084	44.18	gold quality
corpus callosum	UBERON:0002336	44.14	silver quality
cerebellar hemisphere	UBERON:0002245	44.07	silver quality
heart	UBERON:0000948	44.01	gold quality
thoracic aorta	UBERON:0001515	43.66	gold quality
tibial artery	UBERON:0007610	43.62	silver quality
right hemisphere of cerebellum	UBERON:0014890	42.76	silver quality
lung	UBERON:0002048	42.53	silver quality
subcutaneous adipose tissue	UBERON:0002190	42.38	silver quality
substantia nigra	UBERON:0002038	42.31	gold quality
body of pancreas	UBERON:0001150	42.28	silver quality
ascending aorta	UBERON:0001496	42.17	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	42.13	silver quality
right atrium auricular region	UBERON:0006631	41.91	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.43

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.