LINC02378

Summary

LINC02378 (long intergenic non-protein coding RNA 2378, HGNC:53301) is a long non-coding RNA gene on chromosome 12p12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53301
Approved symbol	LINC02378
Name	long intergenic non-protein coding RNA 2378
Location	12p12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256994
Ensembl biotype	lncRNA
Entrez	105369678
RNAcentral	URS0000BC43E2 — lncRNA, 460 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000540399, ENST00000653611, ENST00000657845, ENST00000664390

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000540399 — 8 exons

Exon	Start	End
ENSE00002226348	17584458	17584522
ENSE00002247122	17589706	17589992
ENSE00002253959	17588994	17589090
ENSE00002295511	17586231	17586285
ENSE00002305720	17584223	17584363
ENSE00002316203	17581819	17581936
ENSE00002317333	17509353	17509467
ENSE00002322292	17552767	17552891

Expression profiles

Bgee: expression breadth broad, 55 present calls, max score 81.68.

Top tissues by expression

55 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.68	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	63.30	gold quality
colonic epithelium	UBERON:0000397	61.87	silver quality
prefrontal cortex	UBERON:0000451	55.19	gold quality
islet of Langerhans	UBERON:0000006	53.65	gold quality
gastrocnemius	UBERON:0001388	53.60	gold quality
left testis	UBERON:0004533	53.52	gold quality
testis	UBERON:0000473	53.36	gold quality
right testis	UBERON:0004534	53.09	gold quality
pancreas	UBERON:0001264	51.88	gold quality
blood	UBERON:0000178	51.84	gold quality
monocyte	CL:0000576	51.58	silver quality
placenta	UBERON:0001987	49.46	gold quality
multicellular organism	UBERON:0000468	49.28	gold quality
tibial artery	UBERON:0007610	48.92	gold quality
endometrium	UBERON:0001295	48.65	gold quality
ascending aorta	UBERON:0001496	45.51	silver quality
right hemisphere of cerebellum	UBERON:0014890	45.21	gold quality
Brodmann (1909) area 9	UBERON:0013540	45.09	gold quality
descending thoracic aorta	UBERON:0002345	44.91	gold quality
cerebral cortex	UBERON:0000956	44.71	gold quality
thoracic mammary gland	UBERON:0005200	44.68	gold quality
hypothalamus	UBERON:0001898	44.55	gold quality
putamen	UBERON:0001874	44.13	gold quality
cerebellar hemisphere	UBERON:0002245	44.03	gold quality
right atrium auricular region	UBERON:0006631	43.95	silver quality
anterior cingulate cortex	UBERON:0009835	43.91	gold quality
brain	UBERON:0000955	43.85	gold quality
right frontal lobe	UBERON:0002810	43.67	gold quality
left adrenal gland cortex	UBERON:0035825	43.54	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.44

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.