LINC02395

Summary

LINC02395 (long intergenic non-protein coding RNA 2395, HGNC:53322) is a long non-coding RNA gene on chromosome 12q13.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53322
Approved symbol	LINC02395
Name	long intergenic non-protein coding RNA 2395
Location	12q13.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000257771
Ensembl biotype	lncRNA
Entrez	101927292
RNAcentral	URS000006B30B — lncRNA, 3157 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 62 — 62 lncRNA

ENST00000546821, ENST00000547443, ENST00000547954, ENST00000549734, ENST00000551539, ENST00000653208, ENST00000653417, ENST00000654198, ENST00000654781, ENST00000655750, ENST00000655869, ENST00000655893, ENST00000656286, ENST00000656471, ENST00000656507, ENST00000657051, ENST00000657128, ENST00000657295, ENST00000657679, ENST00000658170, ENST00000658365, ENST00000658656, ENST00000659513, ENST00000659762, ENST00000660860, ENST00000661149, ENST00000661879, ENST00000662741, ENST00000662801, ENST00000663037, ENST00000663596, ENST00000663722, ENST00000663839, ENST00000664040, ENST00000664245, ENST00000664524, ENST00000664860, ENST00000664985, ENST00000665167, ENST00000665234, ENST00000665771, ENST00000666165, ENST00000666502, ENST00000667611, ENST00000667663, ENST00000667671, ENST00000667803, ENST00000668476, ENST00000668699, ENST00000668877, ENST00000669303, ENST00000669347, ENST00000669495, ENST00000669550, ENST00000670023, ENST00000670201, ENST00000670334, ENST00000670552, ENST00000670752, ENST00000670836, ENST00000828038, ENST00000828039

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000546821 — 6 exons

Exon	Start	End
ENSE00002328253	49926081	49926339
ENSE00002336800	49921926	49923681
ENSE00002346261	49911953	49912083
ENSE00002351255	49924936	49925087
ENSE00002402935	49925262	49925388
ENSE00002420785	49923782	49924513

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 79.73.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0427 / max 25.7616, expressed in 19 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
125378	0.0427	19

Top tissues by expression

205 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.73	gold quality
left testis	UBERON:0004533	77.54	gold quality
right testis	UBERON:0004534	76.71	gold quality
testis	UBERON:0000473	74.70	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	69.04	gold quality
right hemisphere of cerebellum	UBERON:0014890	67.40	gold quality
cerebellar hemisphere	UBERON:0002245	67.12	gold quality
cerebellar cortex	UBERON:0002129	67.01	gold quality
cerebellum	UBERON:0002037	65.15	gold quality
cortical plate	UBERON:0005343	63.54	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.15	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.38	gold quality
sural nerve	UBERON:0015488	53.21	silver quality
prefrontal cortex	UBERON:0000451	52.85	gold quality
gall bladder	UBERON:0002110	51.60	gold quality
monocyte	CL:0000576	50.44	silver quality
right frontal lobe	UBERON:0002810	49.90	gold quality
lower lobe of lung	UBERON:0008949	49.43	silver quality
esophagus mucosa	UBERON:0002469	49.35	gold quality
muscle of leg	UBERON:0001383	49.24	gold quality
Brodmann (1909) area 9	UBERON:0013540	49.17	gold quality
gastrocnemius	UBERON:0001388	49.05	gold quality
putamen	UBERON:0001874	48.90	gold quality
nucleus accumbens	UBERON:0001882	48.66	gold quality
frontal cortex	UBERON:0001870	48.62	gold quality
caudate nucleus	UBERON:0001873	48.60	gold quality
brain	UBERON:0000955	48.58	gold quality
neocortex	UBERON:0001950	48.04	gold quality
esophagus	UBERON:0001043	47.63	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	47.35	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.89

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.