LINC02397

Summary

LINC02397 (long intergenic non-protein coding RNA 2397, HGNC:53323) is a long non-coding RNA gene on chromosome 12q22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53323
Approved symbol	LINC02397
Name	long intergenic non-protein coding RNA 2397
Location	12q22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000205056
Ensembl biotype	lncRNA
Entrez	100507616
RNAcentral	URS0000A77068 — lncRNA, 2272 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000504409, ENST00000686471

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000504409 — 2 exons

Exon	Start	End
ENSE00002035266	92482018	92492091
ENSE00002077948	92466451	92467002

Expression profiles

Bgee: expression breadth broad, 63 present calls, max score 67.71.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 1.6406 / max 268.5699, expressed in 156 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
127313	1.1022	96
127312	0.3803	88
206843	0.0926	27
127314	0.0438	24
206842	0.0218	11

Top tissues by expression

172 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
lymph node	UBERON:0000029	67.71	gold quality
vermiform appendix	UBERON:0001154	65.38	gold quality
spleen	UBERON:0002106	64.38	gold quality
tonsil	UBERON:0002372	61.04	gold quality
caecum	UBERON:0001153	60.96	gold quality
anterior cingulate cortex	UBERON:0009835	60.36	gold quality
granulocyte	CL:0000094	59.38	gold quality
small intestine Peyer’s patch	UBERON:0003454	58.43	gold quality
superficial temporal artery	UBERON:0001614	57.98	gold quality
leukocyte	CL:0000738	57.25	gold quality
epithelium of nasopharynx	UBERON:0001951	57.23	gold quality
tendon of biceps brachii	UBERON:0008188	56.95	gold quality
small intestine	UBERON:0002108	55.91	gold quality
germinal epithelium of ovary	UBERON:0001304	55.29	gold quality
blood	UBERON:0000178	54.19	gold quality
monocyte	CL:0000576	53.40	gold quality
endothelial cell	CL:0000115	52.93	gold quality
gingival epithelium	UBERON:0001949	52.22	gold quality
muscle of leg	UBERON:0001383	51.85	gold quality
gastrocnemius	UBERON:0001388	51.83	gold quality
cerebellar vermis	UBERON:0004720	51.41	gold quality
lower lobe of lung	UBERON:0008949	51.24	silver quality
skin of leg	UBERON:0001511	50.20	silver quality
cardia of stomach	UBERON:0001162	49.20	gold quality
superior surface of tongue	UBERON:0007371	48.96	silver quality
left coronary artery	UBERON:0001626	48.75	gold quality
gingiva	UBERON:0001828	48.56	gold quality
gall bladder	UBERON:0002110	47.93	gold quality
coronary artery	UBERON:0001621	47.49	gold quality
adrenal gland	UBERON:0002369	47.39	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	15.26

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.