LINC02405

Summary

LINC02405 (long intergenic non-protein coding RNA 2405, HGNC:53333) is a long non-coding RNA gene on chromosome 12q24.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53333
Approved symbol	LINC02405
Name	long intergenic non-protein coding RNA 2405
Location	12q24.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249345
Ensembl biotype	lncRNA
Entrez	101927592
RNAcentral	URS000075E9AF — lncRNA, 1349 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 39 — 39 lncRNA

ENST00000512624, ENST00000535022, ENST00000540244, ENST00000541419, ENST00000546062, ENST00000651439, ENST00000656033, ENST00000656597, ENST00000656788, ENST00000658026, ENST00000658388, ENST00000660214, ENST00000660588, ENST00000662160, ENST00000664581, ENST00000665379, ENST00000669743, ENST00000670342, ENST00000671361, ENST00000755433, ENST00000755434, ENST00000755435, ENST00000755436, ENST00000755437, ENST00000755438, ENST00000755439, ENST00000755440, ENST00000755441, ENST00000755442, ENST00000755637, ENST00000755638, ENST00000755639, ENST00000755640, ENST00000755641, ENST00000755642, ENST00000755643, ENST00000755644, ENST00000755645, ENST00000755646

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000512624 — 7 exons

Exon	Start	End
ENSE00002022514	126923030	126923205
ENSE00002029996	127060087	127060397
ENSE00002034236	126915203	126915449
ENSE00002050065	126922707	126922959
ENSE00002065322	127000556	127000650
ENSE00002073725	126975839	126975917
ENSE00002082307	127031867	127032066

Expression profiles

Bgee: expression breadth ubiquitous, 115 present calls, max score 79.24.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0709 / max 6.2087, expressed in 45 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
134084	0.0709	45

Top tissues by expression

115 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.24	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.40	gold quality
colonic epithelium	UBERON:0000397	61.25	silver quality
mucosa of transverse colon	UBERON:0004991	61.19	gold quality
rectum	UBERON:0001052	60.24	gold quality
cortical plate	UBERON:0005343	58.91	silver quality
liver	UBERON:0002107	56.36	gold quality
duodenum	UBERON:0002114	56.27	gold quality
monocyte	CL:0000576	56.26	gold quality
spleen	UBERON:0002106	55.63	gold quality
right lobe of liver	UBERON:0001114	55.06	gold quality
ganglionic eminence	UBERON:0004023	54.76	silver quality
islet of Langerhans	UBERON:0000006	54.69	gold quality
skeletal muscle tissue	UBERON:0001134	54.63	gold quality
transverse colon	UBERON:0001157	54.36	gold quality
testis	UBERON:0000473	53.89	gold quality
bone marrow	UBERON:0002371	53.35	silver quality
gall bladder	UBERON:0002110	52.72	gold quality
left testis	UBERON:0004533	52.69	gold quality
intestine	UBERON:0000160	51.54	gold quality
blood	UBERON:0000178	51.50	gold quality
pancreas	UBERON:0001264	51.47	gold quality
lymph node	UBERON:0000029	51.44	silver quality
colon	UBERON:0001155	51.43	gold quality
right testis	UBERON:0004534	51.31	gold quality
myometrium	UBERON:0001296	51.01	gold quality
small intestine	UBERON:0002108	50.72	gold quality
omental fat pad	UBERON:0010414	50.55	gold quality
prefrontal cortex	UBERON:0000451	50.35	gold quality
small intestine Peyer’s patch	UBERON:0003454	49.64	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.27

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.