LINC02421

Summary

LINC02421 (long intergenic non-protein coding RNA 2421, HGNC:53351) is a long non-coding RNA gene on chromosome 12q15.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53351
Approved symbol	LINC02421
Name	long intergenic non-protein coding RNA 2421
Location	12q15
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255970
Ensembl biotype	lncRNA
Entrez	101927901
RNAcentral	URS000024EF03 — lncRNA, 3135 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000542219, ENST00000829389, ENST00000835137

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000542219 — 5 exons

Exon	Start	End
ENSE00002205739	67709047	67710685
ENSE00002257553	67715322	67716203
ENSE00002260645	67718343	67718541
ENSE00002280271	67722379	67722713
ENSE00002292701	67729396	67729475

Expression profiles

Bgee: expression breadth broad, 61 present calls, max score 74.24.

Top tissues by expression

171 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	74.24	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	73.57	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.55	gold quality
sural nerve	UBERON:0015488	59.93	silver quality
muscle of leg	UBERON:0001383	57.12	gold quality
gastrocnemius	UBERON:0001388	56.67	gold quality
stromal cell of endometrium	CL:0002255	53.28	silver quality
tibial nerve	UBERON:0001323	53.22	gold quality
rectum	UBERON:0001052	50.70	gold quality
calcaneal tendon	UBERON:0003701	50.08	silver quality
granulocyte	CL:0000094	48.50	silver quality
skeletal muscle tissue	UBERON:0001134	48.39	gold quality
gall bladder	UBERON:0002110	48.35	silver quality
islet of Langerhans	UBERON:0000006	46.07	silver quality
transverse colon	UBERON:0001157	45.93	gold quality
lymph node	UBERON:0000029	45.80	silver quality
smooth muscle tissue	UBERON:0001135	45.71	silver quality
anterior cingulate cortex	UBERON:0009835	45.36	silver quality
right atrium auricular region	UBERON:0006631	45.33	gold quality
cardiac atrium	UBERON:0002081	45.14	gold quality
left uterine tube	UBERON:0001303	43.97	gold quality
colon	UBERON:0001155	43.69	gold quality
large intestine	UBERON:0000059	43.62	gold quality
heart	UBERON:0000948	43.61	silver quality
body of stomach	UBERON:0001161	43.55	silver quality
anatomical system	UBERON:0000467	43.39	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
tibial artery	UBERON:0007610	43.37	silver quality
popliteal artery	UBERON:0002250	43.32	silver quality
multicellular organism	UBERON:0000468	43.24	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.09

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.