LINC02422

Summary

LINC02422 (long intergenic non-protein coding RNA 2422, HGNC:53352) is a long non-coding RNA gene on chromosome 12p11.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53352
Approved symbol	LINC02422
Name	long intergenic non-protein coding RNA 2422
Location	12p11.21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255760
Ensembl biotype	lncRNA
Entrez	105369723
RNAcentral	URS0000A76CAC — lncRNA, 962 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000535163, ENST00000662662, ENST00000686104, ENST00000687652, ENST00000752257, ENST00000752258, ENST00000752259, ENST00000752260, ENST00000752261

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000535163 — 2 exons

Exon	Start	End
ENSE00004098170	31876966	31877893
ENSE00004098172	31887167	31887218

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 84.32.

FANTOM5 (CAGE): breadth broad, TPM avg 1.3269 / max 91.6264, expressed in 389 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
130399	0.6310	242
130395	0.3990	71
130398	0.2665	86
130396	0.0305	15

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
quadriceps femoris	UBERON:0001377	84.32	gold quality
spleen	UBERON:0002106	80.32	gold quality
lymph node	UBERON:0000029	77.89	gold quality
cerebellar vermis	UBERON:0004720	77.73	gold quality
blood	UBERON:0000178	75.22	gold quality
monocyte	CL:0000576	75.08	gold quality
leukocyte	CL:0000738	74.55	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.30	silver quality
thymus	UBERON:0002370	73.39	silver quality
vermiform appendix	UBERON:0001154	70.44	gold quality
tonsil	UBERON:0002372	68.97	gold quality
bone marrow cell	CL:0002092	68.23	silver quality
granulocyte	CL:0000094	67.92	gold quality
right uterine tube	UBERON:0001302	64.81	gold quality
small intestine Peyer’s patch	UBERON:0003454	64.35	gold quality
small intestine	UBERON:0002108	63.68	gold quality
mucosa of transverse colon	UBERON:0004991	63.07	gold quality
skeletal muscle tissue	UBERON:0001134	61.15	gold quality
cortical plate	UBERON:0005343	61.00	gold quality
fallopian tube	UBERON:0003889	60.24	gold quality
colonic epithelium	UBERON:0000397	60.20	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	60.16	silver quality
bone marrow	UBERON:0002371	59.57	gold quality
muscle tissue	UBERON:0002385	59.19	gold quality
liver	UBERON:0002107	57.20	gold quality
right lobe of liver	UBERON:0001114	57.13	gold quality
hindlimb stylopod muscle	UBERON:0004252	56.67	gold quality
rectum	UBERON:0001052	56.35	gold quality
urinary bladder	UBERON:0001255	55.77	gold quality
calcaneal tendon	UBERON:0003701	54.97	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.89

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.