LINC02427

Summary

LINC02427 (long intergenic non-protein coding RNA 2427, HGNC:53358) is a long non-coding RNA gene on chromosome 4q35.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53358
Approved symbol	LINC02427
Name	long intergenic non-protein coding RNA 2427
Location	4q35.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000271538
Ensembl biotype	lncRNA
Entrez	105377585
RNAcentral	URS0000BC43EE — lncRNA, 1098 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000604660, ENST00000605270, ENST00000696856, ENST00000772711, ENST00000772712, ENST00000772713, ENST00000772714, ENST00000772715, ENST00000772716

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000604660 — 3 exons

Exon	Start	End
ENSE00003466785	184509237	184509325
ENSE00003593651	184509496	184509688
ENSE00003650716	184506918	184507376

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 80.71.

FANTOM5 (CAGE): breadth broad, TPM avg 1.7225 / max 44.5915, expressed in 660 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
55149	1.5674	647
55148	0.1550	72

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
quadriceps femoris	UBERON:0001377	80.71	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	71.95	gold quality
bone marrow cell	CL:0002092	71.90	gold quality
bone marrow	UBERON:0002371	71.81	gold quality
cerebellar vermis	UBERON:0004720	67.75	gold quality
thymus	UBERON:0002370	67.30	silver quality
calcaneal tendon	UBERON:0003701	59.08	gold quality
gall bladder	UBERON:0002110	59.00	gold quality
prefrontal cortex	UBERON:0000451	57.67	gold quality
ventricular zone	UBERON:0003053	57.59	silver quality
skeletal muscle tissue	UBERON:0001134	56.98	gold quality
muscle tissue	UBERON:0002385	56.93	gold quality
lymph node	UBERON:0000029	56.58	gold quality
superior frontal gyrus	UBERON:0002661	56.42	gold quality
temporal lobe	UBERON:0001871	56.31	gold quality
amygdala	UBERON:0001876	56.00	gold quality
corpus callosum	UBERON:0002336	55.90	gold quality
tonsil	UBERON:0002372	55.59	gold quality
nucleus accumbens	UBERON:0001882	55.46	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.42	gold quality
frontal cortex	UBERON:0001870	55.20	gold quality
spinal cord	UBERON:0002240	55.12	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	55.10	gold quality
cortical plate	UBERON:0005343	54.99	silver quality
substantia nigra	UBERON:0002038	54.65	gold quality
hypothalamus	UBERON:0001898	54.47	gold quality
anterior cingulate cortex	UBERON:0009835	54.35	gold quality
cerebral cortex	UBERON:0000956	54.23	gold quality
liver	UBERON:0002107	53.90	silver quality
leukocyte	CL:0000738	53.76	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.73

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.